54031-97-9

Usage

Uses

Used in Marine Algal Biomass Industry:
Pentanoic acid, 2-hydroxy-4-oxo(9CI) is used as a key component in the production of valuable compounds from marine algal biomass, such as Gelidium amansii. Its presence in the biomass contributes to the development of new products and applications in this industry.
Used as a Thermophilic Bacteria Growth Inhibitor:
Pentanoic acid, 2-hydroxy-4-oxo(9CI) is utilized as a growth inhibitor for thermophilic bacteria. Its inhibitory properties help control the growth of these bacteria in various industrial processes, such as in the production of biofuels or in the treatment of wastewater, where the presence of thermophilic bacteria can be problematic.

Upstream product

• 5699-58-1 2,4-dioxo-pentanoic acid 
• 80-71-7 2-hydroxy-3-methylcyclopent-2-en-1-one 
• 2833-24-1 methyl (E)-4-oxo-2-pentenoate 

Relevant academic research and scientific papers

Asymmetric oxidation of 3-alkyl-1,2-cyclopentanediones. Part 2: Oxidative ring cleavage of 3-alkyl-1,2-cyclopentanediones: Synthesis of 2-alkyl-γ-lactone acids

Ti(OiPr)4/diethyl tartrate/tBuOOH system oxidizes 3-alkyl-1,2-cyclopentanediones resulting in hydroxylated ring cleavage products 2-alkyl-γ-lactone acids, in high enantioselectivity (～95% ee) and satisfactory isolated yields (up to 55%).

Assessment of the Active-Site Requirements of 5-Aminolaevulinic Acid Dehydratase: Evaluation of Substrate and Product Analogues as Competitive Inhibitors

The enzyme 5-aminolaevulinic acid dehydratase (ALAD) is resonsible for the synthesis of porphobilinogen (PBG) from two molecules of 5-aminolaevulinic acid (ALA).Porphobilinogen is an important committed intermediate in the biosynthesis of tetrapyrroles.Th

CONDENSATION OF α,γ-DIKETO (OR KETOSUCCINIC) ESTERS WITH GLYOXYLIC ACID

2-Hydroxy-4-keto acids may be conveniently prepared by elimination of the oxalyl moiety, catalyzed by Zn(2+), from 4-carboxy-2-hydroxybutenolides.These are obtained in good yield by the addition of α,γ-diketo esters to sodium glyoxylate.If the α,γ-diketo esters, or ketosuccinic esters, carry an alkyl substituent in the β position their addition to sodium glyoxylate proceeds with the simultaneous splitting of the oxalyl moiety.The corresponding 2-enoic(4-keto or 3-carboxy) acids are obtained in good yields.