54031-97-9

Basic information

• Product Name: Pentanoic acid, 2-hydroxy-4-oxo- (9CI)
• Synonyms: Pentanoic acid, 2-hydroxy-4-oxo- (9CI);Pentanoic acid, 2-hydroxy-4-oxo-;2-hydroxy-4-oxopentanoic acid
• CAS NO: 54031-97-9
• Molecular Formula: C5H8O4
• Molecular Weight: 132.11462
• Product Categories: ACETYLGROUP
• Mol File: 54031-97-9.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Pentanoic acid, 2-hydroxy-4-oxo- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Pentanoic acid, 2-hydroxy-4-oxo- (9CI)(54031-97-9)
• EPA Substance Registry System: Pentanoic acid, 2-hydroxy-4-oxo- (9CI)(54031-97-9)

Safety Data

• Hazardous Substances Data: 54031-97-9(Hazardous Substances Data)

Usage

Uses

2-Hydroxy-4-oxopentanoic acid is a derivative of 4-Oxopentanoic Acid, which is produced from marine algal biomass Gelidium amansii. Thermophilic bacteria growth inhibitor.

Upstream product

• 80-71-7 2-hydroxy-3-methylcyclopent-2-en-1-one 
• 2833-24-1 methyl (E)-4-oxo-2-pentenoate 
• 5699-58-1 2,4-dioxo-pentanoic acid 

Relevant articles and documents

Asymmetric oxidation of 3-alkyl-1,2-cyclopentanediones. Part 2: Oxidative ring cleavage of 3-alkyl-1,2-cyclopentanediones: Synthesis of 2-alkyl-γ-lactone acids

Ti(OiPr)4/diethyl tartrate/tBuOOH system oxidizes 3-alkyl-1,2-cyclopentanediones resulting in hydroxylated ring cleavage products 2-alkyl-γ-lactone acids, in high enantioselectivity (～95% ee) and satisfactory isolated yields (up to 55%).

CONDENSATION OF α,γ-DIKETO (OR KETOSUCCINIC) ESTERS WITH GLYOXYLIC ACID

2-Hydroxy-4-keto acids may be conveniently prepared by elimination of the oxalyl moiety, catalyzed by Zn(2+), from 4-carboxy-2-hydroxybutenolides.These are obtained in good yield by the addition of α,γ-diketo esters to sodium glyoxylate.If the α,γ-diketo esters, or ketosuccinic esters, carry an alkyl substituent in the β position their addition to sodium glyoxylate proceeds with the simultaneous splitting of the oxalyl moiety.The corresponding 2-enoic(4-keto or 3-carboxy) acids are obtained in good yields.