54034-47-8

Upstream product

• 495-40-9 propiophenone 
• 127-08-2 potassium acetate 
• 877-35-0 2-bromo-1-phenylbutan-1-one 
• 2570-63-0 thallium(III) triacetate 
• 64-19-7 acetic acid 
• 1026485-18-6 4-Nitro-benzenesulfonic acid 1-benzoyl-propyl ester 
• 108-24-7 acetic anhydride 
• 622-76-4 1-phenyl-1-butyne 

Downstream Products

• 16183-46-3 (R)-(+)-2-hydroxy-1-phenyl-1-butan-1-one 
• 104426-42-8 (S)-(+)-2-(Acetyloxy)-1-phenyl-1-butanone 
• 105906-50-1 5-ethyl-2-methyl-4-phenyl-oxazole 

Relevant academic research and scientific papers

Sulfur-mediated difunctionalization of internal and terminal alkynes for the synthesis of α-acetoxy ketones

The sulfur-mediated difunctionalization of alkynes is reported to give α-acetoxy ketones in a one-pot operation under mild conditions with 19–92% yield. By using wet potassium acetate as both the aqueous base and nucleophilic reagent, both terminal alkynes and internal alkynes could be converted into the α-acetoxy ketone products.

Synthesis of α-heterosubstituted ketones through sulfur mediated difunctionalization of internal alkynes

Synthesis of α-heterosubstituted ketones was achieved through sulfur mediated difunctionalization of internal alkynes in one pot. The reaction design involves: phenyl substituted internal alkyne attacking triflic anhydride activated diphenyl sulfoxide to

An efficient method for the α-acetoxylation of ketones

α-Acetoxylation of ketones catalyzed by iodobenzene using 30% aqueous hydrogen peroxide and acetic anhydride as the oxidant is an effective and economical method for the preparation of a-acetoxy ketones. The reaction gave the products in good yields witho

A facile synthesis of secondary α-alkoxy or α-acetoxy aromatic ketones

The treatment of HNIB with aromatic ketones and subsequent solvolysis using alcohol or acetic acid in one-pot system makes it possible to give corresponding secondary α-alkoxy or α-acetoxy ketones in high yields.

Synthesis of Oxazoles by the Reaction of Ketones with Iron(III) Solvates of Nitriles

Oxazoles having functionalized carbon substituents at the C-2 position were synthesized in one step by the oxidation of ketones with iron(III) solvates of nitriles, i.e., Fe(RCN)6(ClO4)3(solvate A) or Fe(RCN)6)FeCl4)3(solvate B), in the corresponding nitriles.Keywords oxazole; ketone; oxidation; nitrile; iron(III) nitrile solvate