540490-40-2Relevant academic research and scientific papers
Bridgehead enolates: Substitution and asymmetric desymmetrization of small bridged carbonyl compounds by lithium amide bases
Giblin, Gerard M. P.,Kirk, Douglas T.,Mitchell, Lee,Simpkins, Nigel S.
, p. 1673 - 1675 (2007/10/03)
(Matrix presented) Contrary to expectations, a number of bridged carbonyl compounds undergo facile bridgehead metalation with lithium amide bases. Diketone, lactone, lactam, and imide functions are all demonstrated to participate in this type of "bridgehe
