54057-59-9

Usage

Uses

Used in Pharmaceutical Industry:
4-CINNAMAMIDOBENZOIC ACID is used as an active pharmaceutical ingredient for its potential anti-inflammatory and anti-microbial properties, making it a candidate for the development of new medications to treat various conditions.
Used in Organic Synthesis:
4-CINNAMAMIDOBENZOIC ACID is used as a key intermediate in the synthesis of other organic compounds, contributing to the creation of a wide range of chemical products.
Used in Consumer Products:
4-CINNAMAMIDOBENZOIC ACID is used as a component in consumer products, leveraging its properties to enhance the performance or provide specific benefits in various applications.

InChI:InChI=1/C16H13NO3/c18-15(11-6-12-4-2-1-3-5-12)17-14-9-7-13(8-10-14)16(19)20/h1-11H,(H,17,18)(H,19,20)/b11-6+

Upstream product

• 102-92-1 cinnamoyl chloride 
• 150-13-0 4-amino-benzoic acid 
• 140-10-3 (E)-3-phenylacrylic acid 
• 102-92-1 Cinnamoyl chloride 

Relevant academic research and scientific papers

Synthesis of novel cinnamoyl amides using a solvent-free microwave-assisted method

A novel series of potential biologically active new cinnamoyl amides were synthesized in good yield and short reaction times. We have studied the one-pot, solvent-free reaction of cinnamic acid derivatives with aromatic amines using 1,3-dicyclohexylcarbodiimide under microwave irradiation in the presence of small quantities of dimethylformamide to improve energy transfer.

Design, synthesis and inhibitory activities of 8-(substituted styrolformamido) phenyl-xanthine derivatives on monoamine oxidase B

The design and synthesis of two series of 8-(substituted styrol-formamido)phenyl-xanthine derivatives are described. Their in vitro monoamine oxidase B (MAO-B) inhibition were tested and the effect of substituents on the N-7, phenyl and the substituted positions are discussed. It was observed that compound 9b displayed significant MAO-B inhibition activity and selectivity, fluorine substitution plays a key role in the selectivity of MAO-B inhibition, and the styrol-formamido group at position-3′ may enhance the activity and selectivity of 8-phenyl-xanthine analogues. These results suggest that such compounds may be utilized for the development of new candidate MAO-B inhibitors for treatment of Parkinson's disease.