540738-13-4

Basic information

• Product Name: (R)-4-[(3R,5R,7R,8R,9S,10S,12S,13R,14S,17R)-3-(4,5-Dimethoxy-2-nitro-benzyloxy)-7,12-dihydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-pentanoic acid methyl ester
• CAS NO: 540738-13-4
• Molecular Weight: 617.78
• Mol File: 540738-13-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-4-[(3R,5R,7R,8R,9S,10S,12S,13R,14S,17R)-3-(4,5-Dimethoxy-2-nitro-benzyloxy)-7,12-dihydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-pentanoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-4-[(3R,5R,7R,8R,9S,10S,12S,13R,14S,17R)-3-(4,5-Dimethoxy-2-nitro-benzyloxy)-7,12-dihydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-pentanoic acid methyl ester(540738-13-4)
• EPA Substance Registry System: (R)-4-[(3R,5R,7R,8R,9S,10S,12S,13R,14S,17R)-3-(4,5-Dimethoxy-2-nitro-benzyloxy)-7,12-dihydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-pentanoic acid methyl ester(540738-13-4)

Safety Data

• Hazardous Substances Data: 540738-13-4(Hazardous Substances Data)

Upstream product

• 81-25-4 cholic acid 
• 53413-67-5 6-nitroveratrylbromide 
• 1448-36-8 methyl cholate 

Downstream Products

• 540738-16-7 3-(4,5-dimethoxy-2-nitrobenzyl)cholic acid 

Relevant articles and documents

Design, synthesis and photochemical properties of caged bile acids

Photolabile derivatives of bile acids (8-10 and 13) were synthesized via silver (I) oxide promoted selective etherification of 3α-hydroxyls. Quantitative production of the parent cholic acid was detected from the photolytic mixture of 3-NB-CA (8) in Tris buffered solution. Interestingly, the unexpectedly stable nitroso-hemiacetal intermediate (14) was detected when the photolysis was conducted in methanol. The enzymatic analysis using 7α-HSDH showed 8 and 9 could serve as caged bile acids that might be able to regulate certain biological processes upon UV irradiation.