54078-29-4

Basic information

• Product Name: 1,8-Diazafluoran-9-one
• Synonyms: DFO;CYCLOPENTA[1,2-B:4,3-B']DIPYRIDIN-9-ONE;1,8-Diazafluoran-9-one;1,8-DIAZAFLUOREN-9-ONE;4-5-DIAZAFLUORENONE-0;RARECHEM AQ NN 0271;1,8-Diaza-9-fluorenone;2.1,8-DIAZAFLUORAN-9-ONE
• CAS NO: 54078-29-4
• Molecular Formula: C₁₁H₆N₂O
• Molecular Weight: 182.18
• Product Categories: Fused Ring Systems
• Mol File: 54078-29-4.mol
• Article Data: 1

Chemical Properties

• Melting Point: 229-233 °C
• Boiling Point: 396.3 °C at 760 mmHg
• Flash Point: 196.1 °C
• Appearance: yellow powder
• Density: 1.387 g/cm³
• Vapor Pressure: 1.72E-06mmHg at 25°C
• Refractive Index: 1.688
• Storage Temp.: 2-8°C
• Solubility: acetic acid: 10 mg/mL, clear
• PKA: 0.69±0.20(Predicted)
• Stability: Stable. Incompatible with strong oxidizing agents.
• BRN: 134499
• CAS DataBase Reference: 1,8-Diazafluoran-9-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1,8-Diazafluoran-9-one(54078-29-4)
• EPA Substance Registry System: 1,8-Diazafluoran-9-one(54078-29-4)

Safety Data

• Hazard Codes: Xi
• Safety Statements: 22-24/25
• WGK Germany: 3
• F: 10
• Hazardous Substances Data: 54078-29-4(Hazardous Substances Data)

Usage

Chemical Properties

yellow powder

Uses

1,8-Diazafluoren-9-one is a useful fluorescent reagent for amino acid study.

Purification Methods

Recrystallise it from Me2CO. The oxime has m 119-200o. [Druey & Schmid Helv Chim Acta 33 1080 1950, Beilstein 24 III/IV 622.]

InChI:InChI=1/C11H6N2O/c14-11-9-7(3-1-5-12-9)8-4-2-6-13-10(8)11/h1-6H

Upstream product

• 84-12-8 phanquinone 

Downstream Products

• 244-50-8 1,8-diazafluorene 
• 102290-57-3 3',3'-diphenyl-spiro[cyclopenta[1,2-b;4,3-b']dipyridine-9,2'-oxirane] 

Relevant articles and documents

α,α-disubstituted aromatics and heteroaromatics as cognition enhancers

Cognitive defeciencies or neurological dysfunction in mammals are treated with α,α-disubstituted aromatic or heteroaromatic compounds. The compounds have the formula: STR1 or a salt thereof wherein X and Y are taken together to form a saturated or unsaturated carbocyclic or heterocyclic first ring and the shown carbon in said ring is α to at least one additional aromatic ring or heteroaromatic ring fused to the first ring; one of Het1 is 2, 3 or 4-pyridyl or 2, 4, or 5-pyrimidinyl and the other is selected from (a) 2, 3, or 4-pyridyl, (b) 2, 4, or 5-pyrimidinyl, (c) 2-pyrazinyl, (d) 3, or 4-pyridazinyl, (e) 3, or 4-pyrazolyl, (f) 2, or 3-tetrahydrofuranyl, and (g) 3-thienyl.