540797-44-2Relevant academic research and scientific papers
Chiral Bifunctional Phosphine-Carboxylate Ligands for Palladium(0)-Catalyzed Enantioselective C?H Arylation
Yang, Lei,Neuburger, Markus,Baudoin, Olivier
supporting information, p. 1394 - 1398 (2018/01/05)
Previous enantioselective Pd0-catalyzed C?H activation reactions proceeding via the concerted metalation-deprotonation mechanism employed either a chiral ancillary ligand, a chiral base, or a bimolecular mixture thereof. This study describes th
Palladium-Catalyzed Carbamate-Directed Regioselective Halogenation: A Route to Halogenated Anilines
Moghaddam, Firouz Matloubi,Tavakoli, Ghazal,Saeednia, Borna,Langer, Peter,Jafari, Behzad
, p. 3868 - 3876 (2016/05/24)
This study describes an efficient method for ortho-selective halogenation of N-arylcarbamates under mild conditions for the first time. Although being weakly coordinating, N-arylcarbamates act very well as a removable directing group for activation of C-H bonds. The developed procedure results in extremely valuable halogenated N-arylcarbmates that can further be hydrolyzed to halogenated anilines. The obtained reaction conditions showed broad scope and wide functional group tolerance. All the products were formed in good yields with extremely high selectivity.
Synthesis of 5,6-dihydrophenanthridines via N,O-acetal TMS ethers
Lee, Won-Il,Jung, Jong-Wha,Jang, Jaebong,Yun, Hwayoung,Suh, Young-Ger
, p. 5167 - 5171 (2013/09/02)
A concise and high-yielding protocol for the synthesis of 5,6-dihydrophenanthridines is disclosed. The key feature includes a sequential reduction-cyclization reaction of N-acylcarbamates via N,O-acetal TMS ethers as a stable N-acyliminium ion precursor.
