5408-07-1

Usage

Uses

Used in Organic Synthesis:
ETHYL 4-BROMO-3,5-DIMETHYL-1H-PYRROLE-2-CARBOXYLATE is used as a building block in organic synthesis for constructing more complex molecules. Its unique structure allows for the creation of a variety of chemical entities with diverse applications.
Used in Pharmaceutical Research:
In the pharmaceutical industry, ETHYL 4-BROMO-3,5-DIMETHYL-1H-PYRROLE-2-CARBOXYLATE is used as a key intermediate in the synthesis of drug candidates. Its structural features make it a valuable component in the development of new medications with potential therapeutic benefits.
Used in Biological and Pharmacological Studies:
Due to its structural characteristics, ETHYL 4-BROMO-3,5-DIMETHYL-1H-PYRROLE-2-CARBOXYLATE may have potential biological or pharmacological activities. It is used in research to explore its interactions with biological systems and its potential as a therapeutic agent.
Used in Chemical Research:
ETHYL 4-BROMO-3,5-DIMETHYL-1H-PYRROLE-2-CARBOXYLATE is also utilized in chemical research to study the properties of pyrrole derivatives and their reactivity in various chemical reactions. This helps in understanding the broader scope of applications for this class of compounds.

Upstream product

• 131992-04-6 ethyl 4--3,5-dimethylpyrrole-2-carboxylate 
• 7789-45-9 copper(ll) bromide 
• 73652-60-5 1-benzoyl-4-bromo-2-ethoxycarbonyl-3,5-dimethylpyrrole 

Downstream Products

• 562074-46-8 4-bromo-3,5-dimethyl-pyrrole-2-carboxylic acid 
• 3274-67-7 ethyl 3,5-dimethyl-4-phenyl-1H-pyrrole-2-carboxylate 
• 720708-07-6 4-(4-Carboxy-phenyl)-3,5-dimethyl-1H-pyrrole-2-carboxylic acid ethyl ester 
• 720708-11-2 4-(3-Carboxy-phenyl)-3,5-dimethyl-1H-pyrrole-2-carboxylic acid ethyl ester 
• 29170-87-4 diethyl 3-methyl-pyrrole-2,5-dicarboxylate 
• 89909-42-2 4-bromo-3-methyl-1H-pyrrole-2-carboxylic acid ethyl ester 
• 3284-47-7 ethyl 3-methyl-1H-pyrrole-2-carboxylate 
• 170508-21-1 3,5-Dimethyl-4-phenyl-1H-pyrrole-2-carboxylic acid 
• 124901-16-2 2,7,12,17-tetramethyl-3,8,13,18-tetraphenylporphyrin 
• 73652-60-5 1-benzoyl-4-bromo-2-ethoxycarbonyl-3,5-dimethylpyrrole 

Relevant academic research and scientific papers

THALLIUM AND MERCURY IN PYRROLE CHEMISTRY. USE OF C-THALLIATED AND C-MERCURIATED PYRROLE DERIVATIVES FOR SELECTIVE RING FUNCTIONALISATIONS via ipso-DETHALLIATION AND -DEMERCURIATION REACTIONS

The use of C-thalliated and C-mercuriated pyrroles to achieve selective introduction of various functional groups in a β position is described.High yields of hardly accessible pyrrole derivatives (such as nitropyrrole) can thus be obtained.

Electrophilic Heteroaromatic Substitutions. 2. Mechanism of the Side-Chain Halogenation of Polysubstituted α-Methylpyrroles with Molecular Chlorine

The mechanism of the α-side-chain chlorination with molecular chlorine in dichloromethane or chloroform solution at low temperatures and in the dark of polysubstituted α-methylpyrroles 1-4 has been investigated with regard to the nature of the reagent and to the fate of the attacking as well as the substituent halogen in the reaction products.Careful product analysis was carried out by radiochemical measurements (chlorine exchange), NMR spectra, standard halide ion titration, and preparative layer chromatography (PLC) techniques.The results suggest that the overall process consists of two main steps, i.e., the electrophilic nuclear attack and the subsequent rearrangement of the halogen to the side chain.Halogen migration from nucleus to side chain may occur from either the adjacent β or the vinylogous α' position.The present data provide a considerable extension of the concept of nonconventional electrophilic halogenation of aromatic molecules into the field of pyrroles.