7789-45-9 Usage
Description
Cupric bromide is a kind of inorganic compound obtained through the reaction between copper oxide and hydrobromic acid. It can be used in laser, generating pulse yellow and green light. The cupric bromide laser is an important technology used in dermatology for the treatment of pigmented lesion and vascular lesions. It can also be used in living radical polymerization and as an intensifier in photographic processing. It is also a brominating agent used in organic synthesis. In addition, it is a kind of highly efficient catalyst in the direct alkynylation of azoles.
Chemical Properties
Different sources of media describe the Chemical Properties of 7789-45-9 differently. You can refer to the following data:
1. Copper(II) bromide, CuBr2, [7789-45-9], MW 223.36, MP 498°C, d 4.77, is a black, deliquescent, monoclinic, crystalline material that obtains from warm aqueous solution. At temperatures below 29°C, the green tetrahydrate is produced. Copper(II) bromide is very soluble in water and soluble in alcohol and acetone.
2. Black crystal
Uses
Different sources of media describe the Uses of 7789-45-9 differently. You can refer to the following data:
1. Copper(II) bromide is used as a catalyst in organic reactions, as an intensifier in photography, and as a brominating agent.
2. As intensifier in photography; as brominating agent in organic synthesis; as humidity indicator; as wood preservative; in solid-electrolyte battery; as stabilizer for acetylated polyformaldehyde.
3. Copper(II) bromide is used in photographic processing as an intensifier and as a brominating agent in organic synthesis. It is also used in the coupling of o-iodophenols and aryl acetylenes avoiding the use of palladium. It finds application in the preparation of NK1/NK2 receptor antagonists used in the regulation of tachykinin.
4. Some reported applications of copper bromide are:catalyst in cross coupling reactions.co-catalyst in Sonogashira coupling.Lewis acid in enantioselective addition of alkynes.reducing agent, when complexed by three molecules of pyridine initiators for the controlled polymerization of styrene, methyl acrylate and methyl methacrylate.Reductive homocoupling of α-bromo- α- chlorocarboxylates to dimethyl α, α′ dichlorosuccinate derivatives in presence of CuBr/LiOCH3 in methanol has been reported.
Preparation
Copper(II) bromide is most easily prepared by neutralization of copper(II) oxide, carbonate, or hydroxide with hydrobromic acid. It can also be produced by oxidation of copper metal with bromine water or by reaction of bromine solutions in alcohol with copper powder.
References
Shen, Youqing, Shiping Zhu, and Robert Pelton. Macromolecules 34.10 (2001): 3182-3185.
Rothfleisch, Jeremy E., et al. Dermatologic clinics 20.1 (2002): 1- 18.
Huang, Jianhui, Simon JF Macdonald, and Joseph PA Harrity. Chemical Communications 4 (2009): 436-438.
Besselièvre, Fran?ois, and Sandrine Piguel. Angewandte Chemie International Edition 48.50 (2009): 9553-9556.
General Description
Odorless black solid. Sinks and mixes with water.
Reactivity Profile
Acidic inorganic salts, such as Cupric bromide, are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible. Many of these compounds catalyze organic reactions.
Health Hazard
Inhalation of dust causes irritation of throat and lungs. Ingestion of large amounts causes violent vomiting and purging, intense pain, collapse, coma, convulsions, and paralysis. Contact with solutions causes eye irritation; contact with solid causes severe eye surface injury and skin irritation.
Fire Hazard
Special Hazards of Combustion Products: Irritating hydrogen bromide gas may form in fire.
Flammability and Explosibility
Notclassified
Purification Methods
Crystallise it twice by dissolving it in water (140mL/g), filtering to remove any Cu2Br2, and concentrating under vacuum at 30o until crystals appear. The cupric bromide is then allowed to crystallise by leaving the solution in a vacuum desiccator containing P2O5 [Hope et al. J Chem Soc 5226 1960, Glemser & Sauer in Handbook of Preparative Inorganic Chemistry (Ed. Brauer) Academic Press Vol II p 1009 1965].
Check Digit Verification of cas no
The CAS Registry Mumber 7789-45-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,7,8 and 9 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 7789-45:
(6*7)+(5*7)+(4*8)+(3*9)+(2*4)+(1*5)=149
149 % 10 = 9
So 7789-45-9 is a valid CAS Registry Number.
InChI:InChI=1/2BrH.Cu/h2*1H;/q;;+2/p-2/rBr2Cu/c1-3-2
7789-45-9Relevant articles and documents
Electronic and vibrational structure of copper dibromide
Lorenz, Martin,Bondybey, Vladimir E.
, p. 5429 - 5436 (2002)
Absorption and laser-induced fluorescence spectra of copper dibromide in a solid neon matrix are reported. Similar to those for copper dichloride, electronic transitions between the low-lying so-called ligand field states states are forbidden by the u?g rule, appear as a result of vibronic Herzberg-Teller coupling. The observed transition energies are in good agreement with the adiabatic state energies derived from a recent gas-phase photodetachment study by Wang and co-workers. The matrix study with its much higher resolution yields detailed information about the copper halide electronic states and their vibrational structures.
Bateman, W. E.,Conrad, D. B.
, p. 2553 - 2560 (1915)
Copper (II) halide complexes with NNO tridentate ligand as chromotropic probes; synthesis, structural characterization and spectroscopic properties
Bouwman, Elisabeth,Golchoubian, Hamid,Shirvan, Atie,Siegler, Maxime A.
, (2021)
This study reports chromotropism of two newly synthesized copper(II) complexes of formula [CuLCl2] and [CuLBr2]?MeOH where L = N-(2-pyridylmethyl)-1-hydroxypropylamine. The structure of the complexes was investigated by infrared spectroscopy, electronic absorption spectroscopy, elemental analysis, molar conductance measurements, and thermal analysis. Single Crystal X-ray structure determination reveals both complexes to adopt a distorted square-pyramidal geometry. Their chromotropic properties were investigated using electronic absorption spectroscopy. The complexes are solvatochromic in solvents with different polarities. The aqueous solutions of the complexes exhibit a variety of colors in the pH range of 1.8 to 11.4 showing that the compounds are halochromic. The complexes are also thermochromic and show reversible color changes in different temperatures in dimethyl sulfoxide solutions. The solution study reveals that the observed chromotropism originates from structural changes of the complexes in different conditions.
Aqueous copper-mediated living polymerization: Exploiting rapid disproportionation of CuBr with Me6TREN
Zhang, Qiang,Wilson, Paul,Li, Zaidong,McHale, Ronan,Godfrey, Jamie,Anastasaki, Athina,Waldron, Christopher,Haddleton, David M.
supporting information, p. 7355 - 7363 (2013/07/11)
A new approach to perform single-electron transfer living radical polymerization (SET-LRP) in water is described. The key step in this process is to allow full disproportionation of CuBr/Me6TREN (TREN = tris(dimethylamino)ethyl amine to Cu(0) powder and CuBr2 in water prior to addition of both monomer and initiator. This provides an extremely powerful tool for the synthesis of functional water-soluble polymers with controlled chain length and narrow molecular weight distributions (polydispersity index approximately 1.10), including poly(N-isopropylacrylamide) , N,N-dimethylacrylamide, poly(ethylene glycol) acrylate, 2-hydroxyethyl acrylate (HEA), and an acrylamido glyco monomer. The polymerizations are performed at or below ambient temperature with quantitative conversions attained in minutes. Polymers have high chain end fidelity capable of undergoing chain extensions to full conversion or multiblock copolymerization via iterative monomer addition after full conversion. Activator generated by electron transfer atom transfer radical polymerization of N-isopropylacrylamide in water was also conducted as a comparison with the SET-LRP system. This shows that the addition sequence of l-ascorbic acid is crucial in determining the onset of disproportionation, or otherwise. Finally, this robust technique was applied to polymerizations under biologically relevant conditions (PBS buffer) and a complex ethanol/water mixture (tequila).
