5409-42-7

Usage

Uses

Used in Pharmaceutical Industry:
DECAHYDRO-PYRAZINO[2,3-B]PYRAZINE is used as a key intermediate for the synthesis of various biologically active compounds, contributing to the development of new drugs and pharmaceuticals. Its unique structure allows it to be a versatile component in the creation of molecules with potential therapeutic effects.
Used in Drug Development:
As a building block in the pharmaceutical industry, DECAHYDRO-PYRAZINO[2,3-B]PYRAZINE is utilized in the research and development of new pharmaceuticals. Its incorporation into drug molecules can lead to the discovery of novel treatments for a range of medical conditions.
Used in Research and Development:
DECAHYDRO-PYRAZINO[2,3-B]PYRAZINE's potential applications extend beyond the pharmaceutical industry, as it is also used in various research and development fields. Its unique properties make it a valuable compound for exploring new chemical reactions and syntheses, potentially leading to breakthroughs in material science, chemical engineering, and other related disciplines.

InChI:InChI=1/C14H8Cl4N2O/c15-7-1-2-11-12(3-7)20-14(19-11)6-21-13-5-9(17)8(16)4-10(13)18/h1-5H,6H2,(H,19,20)

Upstream product

• 131543-46-9 Glyoxal 
• 7732-18-5 water 
• 107-15-3 ethylenediamine 
• 74199-09-0 cyclen-glyoxal 
• 4405-13-4 glyoxal trimer dihydrate 

Downstream Products

• 74199-09-0 cyclen-glyoxal 
• 110-85-0 piperazine 

Relevant academic research and scientific papers

Straightforward and mild deprotection methods of N-mono- and N1,N7-functionalised bisaminal cyclens

Strategic removal of the bisaminal bridge of N-mono- and N1,N7-difunctionalised cyclen glyoxal derivatives was carried out via transamination processes with vicinal diamines. These procedures were found to be particularly well-suited for cyclen targets bearing sensitive groups.

A novel synthesis of 1,4,7,10-tetraazacyclododecane by the tandem reaction of a vinylsulfonium salt

1,4,7,10-Tetraazacyclododecane was synthesized through 4 steps by using easily available diphenylsulfonium triflate as a key annulation reagent. The reaction condition was very mild and the yield was high. After oxidation and hydrolysis, 1,4,7,10-Tetraazacyclododecane, which had been proven to be the pivotal precursor for a wide range of MRI contrast reagents, was produced in an overall yield of 31%.

Preparation of hydroxyalkylpiperazinones by reacting an alkylene oxide with decahydropyrazino[2,3-b]pyrazine or its substituted derivatives

The 4-(2-hydroxyalkyl)-2-piperazinones and their substituted derivatives are prepared by reacting a decahydropyrazino[2,3-b]pyrazine or its substituted derivative having at least one active amine hydrogen, with an alkylene oxide having 2 to 4 carbon atoms.

Trans-1,4,5,8-tetranitro-1,4,5,8-tetraazadecalin

The chemical compound, trans-1,4,5,8-tetranitro-1,4,5,8-tetraazadecalin (D), is produced by the reaction of trans-1,4,5,8-tetraazadecalin with sodium nitrite and hydrochloric acid to obtain trans-1,4,5,8-tetranitroso-1,4,5,8-tetraazadecalin, followed by nitration to yield TNAD, useful as an explosive.