5409-94-9Relevant academic research and scientific papers
An eight-membered N,N,S,S-heterocyclic compound: 4,7-bis(4-chlorophenyl)-3,8-di-hydro-1,2,5,6-dithiadiazocine
Rymarczyk, Beate M.,Preut, Hans,Kreher, Richard P.
, p. 931 - 933 (1997)
The eight-membered ring in the title compound, C16H12Cl2N2S2, adopts a non-planar conformation as expected, and the least-squares planes of the 4-substituted aromatic ring form a dihedral angle of 83.
Gas-Solid Chlorination of 4-Phenylthiazole-2(1H)-thione
Nalini, Veerapaneni,Desiraju, Gautam R.
, p. 1046 - 1048 (1987)
The title compound (1) is converted into an unusual chlorophenacyl disulphide (2) through a crystal structure controlled chlorination-oxidation reaction.
An efficient metal-free synthesis of organic disulfides from thiocyanates using poly-ionic resin hydroxide in aqueous medium
Sengupta, Debasish,Basu, Basudeb
supporting information, p. 2277 - 2281 (2013/05/08)
An efficient and metal-free method is described for the preparation of organic disulfides from alkyl and acyl methyl thiocyanates in the presence of poly-ionic resin hydroxide in aqueous medium. Further extension of this protocol has been tested using two different organyl thiocyanates to prepare unsymmetrical disulfides.
Synthesis of imidazolyl dithiocarbamates and their reactions with phenacyl bromides
El'Tsov,Mokrushin,Smirnova,Shafikov
experimental part, p. 882 - 888 (2012/02/05)
The reactions of ethyl (5-carbamoyl-3H-imidazol-4-yl)dithiocarbamate with phenacyl bromides afford the S-alkylation products as a mixture of E/Z-isomers, which undergo cyclization to 5-(2-oxo-4-arylthiazol-3-yl)-1H-imidazole-4- carboxamides under the acti
One-step synthesis of N-acetylcysteine and glutathione derivatives using the Ugi reaction
Zhdanko, Alexander G.,Gulevich, Anton V.,Nenajdenko, Valentine G.
experimental part, p. 4692 - 4702 (2009/10/02)
Fully protected natural and unnatural N-acetylcysteine, dipeptide Cys-Gly, glutathione, and homoglutathione derivatives were synthesized by the Ugi four-component reaction using various benzylthio aldehydes and ketones as carbonyl building blocks. The scope and limitations of the method were investigated. Formation of imidazoline by-products in the Ugi reaction was discussed. 2,2,2-Trifluoroethanol was shown to be a superior reaction media than methanol in some reactions. Also, the 4-methyl-2,6,7-trioxabicyclo[2.2.2]octyl derivative (OBO-ester) of isocyanoacetic acid was shown to be superior to use than ethyl isocyanoacetate as a peptide synthesis precursor in cases when higher reactivity of an isocyanide is required.
Mn(III)-based reactions of alkenes and alkynes with thiols. An approach toward substituted 2,3-dihydro-1,4-oxathiins and simple route to (E)-vinyl sulfides
Nguyen, Van-Ha,Nishino, Hiroshi,Kajikawa, Shougo,Kurosawa, Kazu
, p. 11445 - 11460 (2007/10/03)
The first example using manganese(III) acetate in the reaction of 1,1- diarylethenes with α-mercaptoketones was examined. A mixture of the ethenes and α-mercaptoketones was treated with manganese(III) acetate in acetic acid, affording cycloaddition products in moderate yields, together with substituted products. The reaction may involve the formation of a carbonation and subsequent cyclization to give the substituted 2,3-dihydro-1,4-oxathiin 3. A similar reaction with thioglycolic acid gave 1,4-oxathiolan-2-one 7. While thiyl radicals easily formed by manganese(III) oxidation with ethanethiol or benzenethiol reacted with alkynes to give preferentially (E)- vinyl sulfides 10 in quantitative yields.
