54095-15-7

Upstream product

• 17097-90-4 2-phenylmalonic acid monoethyl ester 
• 1636-25-5 (ethyl)phenylmalonic acid 
• 76-67-5 diethyl ethyl(phenyl)malonate 

Downstream Products

• 114159-15-8 1,3-bis-(3-dimethylamino-propyl)-5-ethyl-5-phenyl-pyrimidine-2,4,6-trione 
• 101938-70-9 2-thio-N,N'-dimethylphenobarbital 
• 27503-51-1 5-ethyl-1-methyl-3,5-diphenyl-barbituric acid 
• 82825-51-2 1,3-dibenzyloxy-5-ethyl-5-phenylbarbituric acid 
• 106993-72-0 N,N,N',N'-Tetraisopropyl-2-(2-phenyl-but-1-enylidene)-malonamide 
• 85432-37-7 5-ethyl-5-phenyl-2-isopropyloxy-4,6-pyrimidinedione 
• 95035-91-9 1,4-Dibenzyl-6-ethyl-6-phenyl-[1,4]diazepane-5,7-dione 
• 668998-52-5 5-ethyl-2-methoxy-1-methyl-5-phenyl-dihydro-pyrimidine-4,6-dione 
• 50-06-6 phenobarbital 
• 69243-48-7 5-ethyldihydro-1-methyl-5-phenyl-4,6(1H,5H)-pyrimidinedione 
• 95035-95-3 6-Ethyl-6-phenyl-[1,4]diazepane-5,7-dione 
• 2923-89-9 5-ethyl-5-phenyl-1-[3-(2-trifluoromethyl-phenothiazin-10-yl)-propyl]-pyrimidine-2,4,6-trione 
• 96068-57-4 1-[3-(2-chloro-phenothiazin-10-yl)-propyl]-5-ethyl-5-phenyl-pyrimidine-2,4,6-trione 
• 96178-10-8 5-ethyl-1-(3-phenothiazin-10-yl-propyl)-5-phenyl-pyrimidine-2,4,6-trione 

Relevant academic research and scientific papers

Anticholinergic compounds, composititons and methods of treatment

Compounds of the formula STR1 wherein the variables are defined in the specification. The compounds and their salts are soft anticholinergic/antisecretory agents especially useful as mydriatics and as antiperspirants.

N-Alkyl barbiturates. A series of compounds for the study of metabolic structure-activity relationships

Many therapeutic agents are metabolised along multiple pathways, but up to now there have been few investigations addressing the question of which chemical features of drugs govern the participation in, and quantitative significance of, different biotransformation pathways. To assess the influence of variations of the chemical structure upon metabolim, a series of novel barbiturate analogues has been synthesized. The N1-monoalkylated and N1,N2-dialkylated phenobarbitones and 2-desoxyphenobarbitones have been synthesized via condensation of ethylphenylmalonic acid derivatives with different N-alkylated ureas or thioureas, and/or by base-catalyzed N-alkylation of different barbituric acids.