54099-19-3

Basic information

• Product Name: N-[2-(dimethylamino)ethyl]tricyclo[3.3.1.1~3,7~]decane-1-carboxamide
• CAS NO: 54099-19-3
• Molecular Formula: C₁₅H₂₆N₂O
• Molecular Weight: 250.3797
• Mol File: 54099-19-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 405.2°C at 760 mmHg
• Flash Point: 198.9°C
• Density: 1.083g/cm³
• Vapor Pressure: 8.89E-07mmHg at 25°C
• Refractive Index: 1.54
• CAS DataBase Reference: N-[2-(dimethylamino)ethyl]tricyclo[3.3.1.1~3,7~]decane-1-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[2-(dimethylamino)ethyl]tricyclo[3.3.1.1~3,7~]decane-1-carboxamide(54099-19-3)
• EPA Substance Registry System: N-[2-(dimethylamino)ethyl]tricyclo[3.3.1.1~3,7~]decane-1-carboxamide(54099-19-3)

Safety Data

• Hazardous Substances Data: 54099-19-3(Hazardous Substances Data)

Upstream product

• 828-51-3 1-Adamantanecarboxylic acid 
• 108-00-9 N,N-dimethylethylenediamine 
• 2094-72-6 1-Adamantanecarbonyl chloride 

Relevant articles and documents

C H Bond Arylation of Diamondoids Catalyzed by Palladium(II) Acetate

We have developed an effective approach to 1,2-disubstituted diamondoids by palladium(II) acetate catalyzed functionalization of C H bond. Selective mono-arylation of the adamantane framework was achieved using picolylamide as a directing group in yields up to 87 %. Kinetic studies in combination with deuterium labeling experiments, competitive experiments and mass spectrometry contribute to the mechanistic understanding of the arylation process of alkanes with number of C H bonds neighboring the directing group. Triflic anhydride promoted cyclization of the directing group generates imidazo[1,5-a]pyridine derivatives. Acid-mediated removal of the directing group provides access to 2-aryl diamondoid carboxylic acids, which are common precursors for the synthesis of various bioactive compounds (drug candidates). (Figure presented.) .