54114-52-2

Basic information

• Product Name: 2-chloroethyl bromomethanesulfonate
• Synonyms: Methanesulfonic acid, bromo-, 2-chloroethyl ester
• CAS NO: 54114-52-2
• Molecular Formula: C₃H₆BrClO₃S
• Molecular Weight: 237.4999
• Mol File: 54114-52-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 330°C at 760 mmHg
• Flash Point: 153.4°C
• Density: 1.826g/cm³
• Vapor Pressure: 0.000329mmHg at 25°C
• Refractive Index: 1.512
• CAS DataBase Reference: 2-chloroethyl bromomethanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloroethyl bromomethanesulfonate(54114-52-2)
• EPA Substance Registry System: 2-chloroethyl bromomethanesulfonate(54114-52-2)

Safety Data

• Hazardous Substances Data: 54114-52-2(Hazardous Substances Data)

Upstream product

• 10099-08-8 bromomethanesulfonyl chloride 
• 107-07-3 2-chloro-ethanol 

Relevant articles and documents

2-Haloethylating Agents for Cancer Chemoterapy. 2-Haloethyl Sulfonates

Because certain (2-chloroethyl)triazenes and (2-haloethyl)nitrosoureas have high antineoplastic activity, 2-chloroethyl and 2-fluoroethyl sulfonates were prepared to try to develop additional types of 2-haloethylating agents.In this initial study, it was demonstrated that antineoplastic activity much superior to that of the prototype, 2-chloroethyl methanesulfonate, could be found among 2-chloroethyl sulfonates.Among a variety of 2-chloroethyl alkane- and arenesulfonates, several substituted methanesulfonates displayed significant activity agains P388 leukemia in mice; the chloromethanesulfonat e showed high activity (T/C = 218percent).None of the arenesulfonates were active in this test.