54132-35-3

Basic information

• Product Name: 3-Quinolinecarboxylic acid, 7-chloro-1,4-dihydro-4-oxo-, ethyl ester
• CAS NO: 54132-35-3
• Molecular Formula: C12H10ClNO3
• Molecular Weight: 251.669
• Mol File: 54132-35-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Quinolinecarboxylic acid, 7-chloro-1,4-dihydro-4-oxo-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Quinolinecarboxylic acid, 7-chloro-1,4-dihydro-4-oxo-, ethyl ester(54132-35-3)
• EPA Substance Registry System: 3-Quinolinecarboxylic acid, 7-chloro-1,4-dihydro-4-oxo-, ethyl ester(54132-35-3)

Safety Data

• Hazardous Substances Data: 54132-35-3(Hazardous Substances Data)

Upstream product

• 108-42-9 3-chloro-aniline 
• 3412-99-5 2-(3-chlorophenylamino)methylenemalonic acid diethyl ester 

Downstream Products

• 23833-97-8 7-chloro-4(1H)-oxoquinoline 
• 86-98-6 4,7-dichloroquinoline 
• 1235305-69-7 7-chloro-4-oxo-N'-(2,5-dimethoxyphenyl)-1,4-dihydroquinoline-3-carboxamide 

Relevant articles and documents

Synthesis of Fused Pyrimidinone and Quinolone Derivatives in an Automated High-Temperature and High-Pressure Flow Reactor

Fused pyrimidinone and quinolone derivatives that are of potential interest to pharmaceutical research were synthesized within minutes in up to 96% yield in an automated Phoenix high-temperature and high-pressure continuous flow reactor. Heterocyclic scaffolds that are either hard to synthesize or require multisteps are readily accessible using a common set of reaction conditions. The use of low-boiling solvents along with the high conversions of these reactions allowed for facile workup and isolation. The methods reported herein are highly amenable for fast and efficient heterocycle synthesis as well as compound scale-ups.