54145-20-9Relevant academic research and scientific papers
Copper-Catalyzed Direct, Regioselective Arylamination of N-Oxides: Studies to Access Conjugated π-Systems
Biswas, Aniruddha,Karmakar, Ujjwal,Nandi, Shiny,Samanta, Rajarshi
, p. 8933 - 8942 (2017/09/11)
An efficient copper(I)-catalyzed direct regioselective arylamination of various heterocyclic N-oxides was achieved successfully under redox-neutral conditions using anthranils as arylaminating reagents. The developed protocol is simple, straightforward, and economic with a broad range substrate scope. The dual functional groups in the final molecules were utilized to construct structurally and functionally diverse nitrogen-containing organic π-conjugated systems.
Synthesis of 2-Alkenylquinoline by Reductive Olefination of Quinoline N-Oxide under Metal-Free Conditions
Xia, Hong,Liu, Yuanhong,Zhao, Peng,Gou, Shaohua,Wang, Jun
supporting information, p. 1796 - 1799 (2016/05/19)
Synthesis of 2-alkenylquinoline by reductive olefination of quinoline N-oxide under metal-free conditions is disclosed. Practically, the reaction could be performed with quinoline as starting material via a one-pot, two-step process. A possible mechanism is proposed that involves a sequential 1,3-dipolar cycloaddition and acid-assisted ring opening followed by a dehydration process.
Compounds to treat alzheimer's disease
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, (2008/06/13)
The present invention is substituted amines of formula (XV) useful in treating Alzheimer's ease and other similar dise
