54149-39-2

Basic information

• Product Name: Tpc-A014
• Synonyms: o-(2-Methoxy-ethyl)-hydroxylamine;Tpc-A014
• CAS NO: 54149-39-2
• Molecular Formula: C₃H₉NO₂
• Molecular Weight: 91.1091
• Mol File: 54149-39-2.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 157.476°C at 760 mmHg
• Flash Point: 61.051°C
• Appearance: /
• Density: 0.965g/cm³
• Vapor Pressure: 2.749mmHg at 25°C
• Refractive Index: 1.401
• Storage Temp.: Refrigerator, Under inert atmosphere
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• PKA: 4.27±0.70(Predicted)
• CAS DataBase Reference: Tpc-A014(CAS DataBase Reference)
• NIST Chemistry Reference: Tpc-A014(54149-39-2)
• EPA Substance Registry System: Tpc-A014(54149-39-2)

Safety Data

• Hazardous Substances Data: 54149-39-2(Hazardous Substances Data)

Usage

Uses

O-2-Methoxyethylhydroxylamine can be prepared to use as antagonists of the adenosine A2a receptor to treat diseases or conditions in which the adenosine A2a receptor activity is implicated.

InChI:InChI=1/C3H9NO2/c1-5-2-3-6-4/h2-4H2,1H3

Upstream product

• 54149-18-7 2-(2-Methoxy-ethoxy)-isoindole-1,3-dione 

Downstream Products

• 1032818-72-6 (2-methoxyethoxy)-carbamic acid 4-nitro-phenyl ester 
• 1177368-31-8 (E)-2-amino-7-(4-fluoro-2-(6-methoxypyridin-2-yl)phenyl)-4-methyl-7,8-dihydroquinazolin-5(6H)-one O-2-methoxyethyloxime 
• 1443102-65-5 4-((3aS,7aS)-3-(4-cyano-3-(trifluoromethyl)phenyl)-2-oxooctahydro-1H-benzo[d]imidazol-1-yl)-2-fluoro-N-(2-methoxyethoxy)benzamide 
• 1091608-25-1 C₄₀H₄₅N₃O₇Si 
• 41776-68-5 3-Formylrifamycin SV-O-Methoxyaethylenoxim 
• 55634-46-3 2-[1-(2-Methoxy-ethoxyamino)-propylidene]-5,5-dimethyl-cyclohexane-1,3-dione 

Relevant articles and documents

Radical C(sp3)-H Heck-type Reaction of N-Alkoxybenzimidoyl Chlorides with Styrenes to Construct Alkenols

We report the first radical C(sp3)-H Heck-type reaction of aliphatic alcohols for selective δ- and ?-alkenol synthesis by photoredox catalysis. N-Alkoxybenzimidoyl chlorides are developed as novel alkoxyl radical precursors with tunable redox potentials. Various alkenols can be constructed by the inert C(sp3)-H Heck-type reaction of 4-cyano-N-alkoxybenzimidoyl chlorides with styrene derivatives under redox-neutral conditions, which can be performed on the gram scale and can be easily derivatized.

OXIM DERIVATIVES AS HSP90 INHIBITORS

The invention relates to HSP90 inhibiting compounds consisting of the formula: (I) wherein the variables are as defined herein. The invention also relates to pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.

CHEMOKINE RECEPTOR BINDING COMPOUNDS

The present invention relates to chemokine receptor binding compounds, pharmaceutical compositions and their use. More specifically, the present invention relates to modulators of chemokine receptor activity, preferably modulators of CCR5. Thesd compounds demonstrate protective effects against infection of target cells by a human immunodeficiency virus (HIV).