5415-98-5Relevant academic research and scientific papers
PYRAZOLO AND TRIAZOLO BICYCLIC COMPOUNDS AS JAK KINASE INHIBITORS
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Page/Page column 110, (2019/02/15)
The invention provides compounds of formula (I) or a pharmaceutically-acceptable salt thereof, wherein the variables are defined in the specification, that are inhibitors of JAK kinases, particularly JAK3. The invention also provides crystalline forms, ph
NOVEL PYRIMIDINE DERIVATIVE FOR INHIBITING THE GROWTH OF CANCER CELLS
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Page/Page column 20-21, (2011/09/15)
The present invention provides a novel pyrimidine derivative or pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising same, which can effectively inhibit the growth of cancer cells induced by the overexpression of EGFR incl
NOVEL AMIDE DERIVATIVE FOR INHIBITING THE GROWTH OF CANCER CELLS
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Page/Page column 60-61, (2009/01/24)
The present invention provides a novel amide derivative and a pharmaceutically acceptable salt thereof which selectively and effectively inhibits the growth of cancer cells induced by the overexpression of an epidermal growth factor receptor and also prevents the development of drug resistance caused by the mutation of EGFR tyrosine kinase, and a pharmaceutical composition comprising same as an active ingredient.
3-Pyrazolidinone derivatives
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, (2008/06/13)
3-Pyrazolidinone compounds having a solubility of at least 12 grams/liter in an aqueous medium of pH 9 of the formula: STR1 wherein R is a mononuclear phenyl group having substituents in the 3, 4, or 5 positions with a total of no more than 4 non-metallic
