541506-87-0

Upstream product

• 541506-86-9 ethyl (2E)-8-tert-butyldimethylsilyloxy-2-methyloct-2-en-6-ynoate 
• 541507-02-2 (E)-8-[(tert-butyldimethylsilyl)oxy]-2-methyloct-2-en-6-yn-1-ol 
• 135717-46-3 6-tert-butyldimethylsilyloxyhex-4-yn-1-ol 
• 541507-03-3 (2E)-8-tert-butyldimethylsilyloxy-1-tert-butyldiphenylsilyloxy-2-methyloct-2-en-6-yne 

Relevant academic research and scientific papers

Synthesis of macrocyclic precursors of phomactins using 2,3-Wittig rearrangements

The combination of a 2,3-Wittig rearrangement of a suitably substituted cyclohexenylmethyl propargyl ether with a subsequent conversion of the alkyne to a trisubstituted alkene and cyclisation via intramolecular sulfone alkylation has proved to be a usefu

Approaches to the total synthesis of phomactins

The macrocyclic triene 34, an advanced intermediate for synthesis of phomactins, has been synthesized using the 2,3-Wittig rearrangement of the propargylic ether 21 as a key step.