541507-03-3

Basic information

• Product Name: (2E)-8-tert-butyldimethylsilyloxy-1-tert-butyldiphenylsilyloxy-2-methyloct-2-en-6-yne
• Synonyms: (2E)-8-tert-butyldimethylsilyloxy-1-tert-butyldiphenylsilyloxy-2-methyloct-2-en-6-yne
• CAS NO: 541507-03-3
• Molecular Weight: 506.876
• Mol File: 541507-03-3.mol

Chemical Properties

• CAS DataBase Reference: (2E)-8-tert-butyldimethylsilyloxy-1-tert-butyldiphenylsilyloxy-2-methyloct-2-en-6-yne(CAS DataBase Reference)
• NIST Chemistry Reference: (2E)-8-tert-butyldimethylsilyloxy-1-tert-butyldiphenylsilyloxy-2-methyloct-2-en-6-yne(541507-03-3)
• EPA Substance Registry System: (2E)-8-tert-butyldimethylsilyloxy-1-tert-butyldiphenylsilyloxy-2-methyloct-2-en-6-yne(541507-03-3)

Safety Data

• Hazardous Substances Data: 541507-03-3(Hazardous Substances Data)

Upstream product

• 58479-61-1 tert-butylchlorodiphenylsilane 
• 541507-02-2 (E)-8-[(tert-butyldimethylsilyl)oxy]-2-methyloct-2-en-6-yn-1-ol 
• 76782-82-6 tert-Butyldimethyl(prop-2-ynyloxy)silane 
• 541506-86-9 ethyl (2E)-8-tert-butyldimethylsilyloxy-2-methyloct-2-en-6-ynoate 
• 135717-46-3 6-tert-butyldimethylsilyloxyhex-4-yn-1-ol 

Downstream Products

• 541506-87-0 (6E)-8-tert-butyldiphenylsilyloxy-7-methyloct-6-en-2-yn-1-ol 

Relevant articles and documents

Synthesis of macrocyclic precursors of phomactins using 2,3-Wittig rearrangements

The combination of a 2,3-Wittig rearrangement of a suitably substituted cyclohexenylmethyl propargyl ether with a subsequent conversion of the alkyne to a trisubstituted alkene and cyclisation via intramolecular sulfone alkylation has proved to be a usefu

Approaches to the total synthesis of phomactins

The macrocyclic triene 34, an advanced intermediate for synthesis of phomactins, has been synthesized using the 2,3-Wittig rearrangement of the propargylic ether 21 as a key step.