54151-38-1

Basic information

• Product Name: 2-Propanone, 1-(1-pyrrolidinyl)- (9CI)
• Synonyms: 2-Propanone, 1-(1-pyrrolidinyl)- (9CI);1-(1-pyrrolidinyl)-2-Propanone;1-(Pyrrolidin-1-yl)propan-2-one
• CAS NO: 54151-38-1
• Molecular Formula: C₇H₁₃NO
• Molecular Weight: 127.18422
• Product Categories: ACETYLGROUP
• Mol File: 54151-38-1.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Propanone, 1-(1-pyrrolidinyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propanone, 1-(1-pyrrolidinyl)- (9CI)(54151-38-1)
• EPA Substance Registry System: 2-Propanone, 1-(1-pyrrolidinyl)- (9CI)(54151-38-1)

Safety Data

• Hazardous Substances Data: 54151-38-1(Hazardous Substances Data)

Usage

General Description

2-Propanone, 1-(1-pyrrolidinyl)- (9CI), also known as α-PVP, is a synthetic cathinone that belongs to the family of psychoactive designer drugs known as synthetic cathinones. It is a potent stimulant with similar effects to other cathinones, such as increased energy, euphoria, and heightened alertness. This chemical is commonly abused for its psychostimulant effects and is often used recreationally as a party drug. However, its use is associated with a range of negative side effects, including paranoia, agitation, and hallucinations, and it has been linked to numerous adverse health consequences. The recreational use of α-PVP has been banned in several countries due to its potential for abuse and harmful effects on users.

Upstream product

• 123-75-1 pyrrolidine 
• 116-09-6 hydroxy-2-propanone 
• 215376-79-7 1-<(2'-carboxy)pyrrolidinyl>-1-deoxy-D-fructose 

Downstream Products

• 101455-06-5 (E)-4-(4-Methoxy-phenyl)-1-pyrrolidin-1-yl-but-3-en-2-ol 

Relevant articles and documents

Monitoring carbonyl-amine reaction and enolization of 1-hydroxy-2- propanone (acetol) by FTIR spectroscopy

Infrared absorption bands characteristic of the aldehydo, keto, and enediol forms of 1-hydroxy-2-propanone (acetol) were identified and used to study the effect of solvent on the absorption frequencies and the effect of temperature and acid/base catalysis on the enolization reactions. The data indicated that, in addition to water, acids and bases can catalyze the enolization of 1-hydroxy-2-propanone and that the temperature inversely effects the rate of enolization under basic conditions. However, under acidic conditions, increasing the temperature favors the enolization process. In addition, the reaction of 1-hydroxy-2-propanone with a primary and a secondary amine was also monitored by Fourier transform infrared spectroscopy. The data indicated that at room temperature the rate of amine reaction was faster than the rate of its catalysis of enolization; however, below room temperature, the rate of base-catalyzed enolization became comparable with the rate of carbonyl-amine reaction forming both Heyns and Amadori adducts.