54161-37-4

Upstream product

• 74113-24-9 [1-(4-Chloro-phenyl)-3-ethoxy-1H-isoindol-1-yl]-acetic acid methyl ester 
• 26859-66-5 1-(4-chlorophenyl)-3-ethoxy-1H-isoindole 

Downstream Products

• 40593-75-7 3-(4-Chlorophenyl)-3-(4'-chlorophenacyl)phthalimidine 
• 74164-78-6 (αRS,1RS)-α,1-Bis(4-chlorophenyl)isoindoline-1-ethanol 
• 55516-88-6 (αS,1S)-(+)-α,1-Bis(4-chlorophenyl)isoindoline-1-ethanol 
• 55516-87-5 (αR,1R)-(-)-α,1-Bis(4-chlorophenyl)isoindoline-1-ethanol 

Relevant academic research and scientific papers

Stereoselective Synthesis and Relative and Absolute Configuration of α,1-Bis(4-chlorophenyl)isoindoline-1-ethanol

When 1-(4-chlorophenyl)-1-(4'-chlorophenacyl)-3-ethoxy-1H-isoindole (2) was reduced in the presence of diborane (αRS,1RS)-α,1-bis(4-chlorophenyl)isoindoline-1-ethanol (3a) was isolated in 88percent yield.The crude reduction product also contained the seco