54186-35-5

Upstream product

• 23180-28-1 6-methoxy-1-(3-hydroxy-4-methoxybenzyl)-1,2,3,4,5,8-hexahydroisoquinoline 
• 74007-21-9 N-<2-(3-methoxyphenyl)ethyl>(3-hydroxy-4-methoxyphenyl)acetamide 
• 23180-27-0 1-(3'-hydroxy-4'-methoxy-benzyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline 
• 1131-94-8 homoisovanillic acid 
• 74007-25-3 1-(2-Bromo-5-hydroxy-4-methoxy-benzyl)-1,3,4,5,7,8-hexahydro-2H-isoquinolin-6-one 

Downstream Products

• 54186-36-6 1-(2'-bromo-4'-methoxy-5'-hydroxybenzyl)-2-formyl-1,3,4,6,7,8-hexahydroisoquinolin-6-one 
• 74007-24-2 1-(2'-bromo-4'-methoxy-5'-hydroxybenzyl)-2-formyl-1,3,4,5,7,8-hexahydroisoquinolin-6-one 

Relevant academic research and scientific papers

Synthetic Opium Alkaloids and Derivatives. A Short Total Synthesis of (+/-)-Dihydrothebainone, (+/-)-Dihydrocodeinone, and (+/-)-Nordihydrocodeinone as an Approach to a Practical Synthesis of Morphine, Codeine, and Congeners.

Racemic dihydrothebainone (19), nordihydrocodeinone (21), and dihydrocodeinone (22) were synthesized in high overall yield from 3-methoxyphenethylamine (4), via the key intermediate (+/-)-1-bromonordihydrothebainone (18); the route utilized unprotected ph