23180-27-0

Basic information

• Product Name: 1-(3'-hydroxy-4'-methoxy-benzyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline
• Synonyms: 1-(3'-hydroxy-4'-methoxy-benzyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline
• CAS NO: 23180-27-0
• Molecular Weight: 299.37
• Mol File: 23180-27-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-(3'-hydroxy-4'-methoxy-benzyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3'-hydroxy-4'-methoxy-benzyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline(23180-27-0)
• EPA Substance Registry System: 1-(3'-hydroxy-4'-methoxy-benzyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline(23180-27-0)

Safety Data

• Hazardous Substances Data: 23180-27-0(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 1275589-14-4 C₂₁H₂₃NO₅ 
• 1033384-69-8 C₂₀H₂₃NO₅ 
• 2039-67-0 2-(3-methoxyphenyl)-1-ethanamine 
• 1131-94-8 homoisovanillic acid 
• 74007-21-9 N-<2-(3-methoxyphenyl)ethyl>(3-hydroxy-4-methoxyphenyl)acetamide 

Downstream Products

• 23180-28-1 6-methoxy-1-(3-hydroxy-4-methoxybenzyl)-1,2,3,4,5,8-hexahydroisoquinoline 
• 74007-25-3 1-(2-Bromo-5-hydroxy-4-methoxy-benzyl)-1,3,4,5,7,8-hexahydro-2H-isoquinolin-6-one 
• 74007-23-1 1-(2'-bromo-4'-methoxy-5'-hydroxybenzyl)-2-formyl-6-ketal-1,3,4,5,7,8-hexahydroisoquinoline 
• 74007-22-0 C₂₀H₂₅NO₅ 
• 74007-24-2 1-(2'-bromo-4'-methoxy-5'-hydroxybenzyl)-2-formyl-1,3,4,5,7,8-hexahydroisoquinolin-6-one 
• 54186-36-6 1-(2'-bromo-4'-methoxy-5'-hydroxybenzyl)-2-formyl-1,3,4,6,7,8-hexahydroisoquinolin-6-one 
• 54186-35-5 1-(2-bromo-5-hydroxy-4-methoxy-benzyl)-1,3,4,7,8,8a-hexahydro-2H-isoquinolin-6-one 
• 58780-17-9 5-(2-formyl-6-methoxy-1,2,3,4,5,8-hexahydro-isoquinolin-1-ylmethyl)-2-methoxy-phenol 

Relevant articles and documents

One-Pot Preparation of Hexahydroisoquinolines from Amides

The present invention provides an efficient process for the preparation of hexahydroisoquinolines from amides. In particular, the invention provides a good yielding, one-pot process for the synthesis of hexahydroisoquinolines.

Preparation of chiral 1-benzyl-1,2,3,4-tetrahydroisoquinolines by optical resolution

In a short total synthesis of morphinan compounds, derivatives of 1-benzyl-1,2,3,4-tetrahydroisoquinoline are produced. Certain of these compounds, although highly aromatic and functionalized, can be optically resolved. The optically active enantiomers can serve as important intermediates for both natural and unnatural opioids.