54196-63-3

Usage

Molecular structure

The compound has a heterocyclic structure with a triazole ring and a benzoyl group attached to an isoindole core.

Functional groups

The compound contains a chlorine atom and a methyl group as substituents.

Biological activity

The compound has potential biological activity and may be used in pharmaceutical research and development.

Handling and storage

It is important to handle and store this chemical with care due to possible associated hazards.

Upstream product

• 136918-14-4 phthalimide 
• 38150-27-5 5-chloro-2-[3-(hydroxymethyl)-5-methyl-4H-1,2,4-triazol-4-yl] benzophenone 
• 1972-28-7 diethylazodicarboxylate 

Downstream Products

• 61955-42-8 N-<<4-(2-Benzoyl-4-chlorophenyl)-5-<2-(dimethylamino)ethyl>-4H-1,2,4-triazol-3-yl>methyl>phthalimide 
• 28981-97-7 alprazolam 
• 60218-33-9 8-chloro-1-<2-(dimethylamino)ethyl>-6-phenyl-4H-s-triazolo<4,3-a><1,4>benzodiazepine p-toluenesulfonate 
• 33887-02-4 6-(2-chloro-phenyl)-1-methyl-8-nitro-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepine 
• 28911-01-5 triazolam 

Relevant academic research and scientific papers

Novel synthesis of the pharmacologically important 1-substituted-6-phenyl-4H-s-triazolo[4,3-α][1,4]benzodiazepines

Several 6-phenyl-4H-s-triazolo[4,3-α][1,4]benzodiazepines have useful biological activity both in experimental animals and in man. This manuscript describes a novel synthesis of these compounds from intermediates that do not have a pre-formed benzodiazepine ring system.

2-[3-(Phthalimidomethyl)-5-methyl-4H-1,2,4-triazol-4-yl]benzophenones

A process to make 6-phenyl-4H-s-triazolo[4,3-a][1,4]-benzodiazepines by converting 2-[3-(hydroxymethyl)-4H-1,2,4-triazol-4-yl]benzophenones to 2-[3-[(phthalimido or methanesulfonyl)methyl]-4H-1,2,4-triazol-4-yl]benzophenones and converting these compounds to the highly active 6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepines useful as tranquilizers and sedatives.