54197-78-3

Upstream product

• 93-07-2 Veratric acid 
• 106-41-2 4-bromo-phenol 
• 39856-08-1 3,4-dimethoxy-cinnamoyl chloride 
• 56492-66-1 (E)-1-(5-bromo-2-hydroxyphenyl)-3-(3,4-dimethoxyphenyl)prop-2-en-1-one 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 1450-75-5 5-Bromo-2-hydroxyacetophenone 

Downstream Products

• 1459286-58-8 tert-butyl 4-(2-(3,4-dimethoxyphenyl)-4-oxo-4H-chromen-6-yl)piperazine-1-carboxylate 
• 36768-27-1 6-amino-2-(3,4-dimethoxyphenyl)-4H-chromen-4-one 
• 1609456-15-6 6-amino-2-(3,4-dihydroxyphenyl)-4H-chromen-4-one 

Relevant academic research and scientific papers

A novel one-pot synthesis of flavones

In this paper, a one-pot facile route for the BiCl3/RuCl3-mediated synthesis of functionalized flavones is described, including: (i) intermolecularortho-acylation of substituted phenols with cinnamoyl chlorides, and (ii) intramolecular cyclodehydrogenation of the resultingo-hydroxychalcones. The reaction conditions are discussed herein.

Copper-mediated trimethylsilyl azide in amination of bromoflavonoids to synthesize unique aminoflavonoids

Aminoflavonoids are unique antioxidants comparing to other abundant flavonoids in nature. Their syntheses and biological activities were scarcely reported. An effectively copper-mediated amination of the corresponding bromoflavonoids to synthesize a serie

COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY

Provided herein are compounds, compositions thereof and uses therewith for treating spinal muscular atrophy.