542-29-0

Usage

Uses

Used in Pharmaceutical Industry:
Tetrahydro-4H-1,3,5-oxadiazin-4-one serves as a key intermediate in the development of various pharmaceuticals. Its incorporation into drug molecules can enhance their therapeutic properties, making it a valuable component in the creation of novel medications.
Used in Agrochemical Industry:
In the agrochemical sector, tetrahydro-4H-1,3,5-oxadiazin-4-one is utilized as a building block for the synthesis of compounds with pesticidal or herbicidal properties. Its unique structure allows for the design of effective agents that can protect crops and enhance agricultural productivity.
Used in Organic Synthesis:
As an intermediate in organic synthesis, tetrahydro-4H-1,3,5-oxadiazin-4-one contributes to the creation of a wide range of chemical compounds. Its reactivity and structural features make it a useful component in the synthesis of various organic molecules for different applications.
Used in Medicinal Chemistry:
Tetrahydro-4H-1,3,5-oxadiazin-4-one plays a significant role in medicinal chemistry, where it is employed in the design and synthesis of bioactive molecules. Its potential applications in drug development highlight its importance in the discovery of new therapeutic agents.

InChI:InChI=1/C3H6N2O2/c6-3-4-1-7-2-5-3/h1-2H2,(H2,4,5,6)

Upstream product

• 7388-44-5 3,5-bis(methoxymethyl)perhydro-1,3,5-oxadiazin-4-one 

Relevant academic research and scientific papers

Quantitative and qualitative 1H, 13C, and 15N NMR spectroscopic investigation of the urea-formaldehyde resin synthesis

Urea-formaldehyde resins are bulk products of the chemical industry. Their synthesis involves a complex reaction network. The present work contributes to its elucidation by presenting results from detailed NMR spectroscopic studies with different methods. Besides1H NMR and13C NMR, 15N NMR spectroscopy is also applied.15N-enriched urea was used for the investigations. A detailed NMR signal assignment and a model of the reaction network of the hydroxymethylation step of the synthesis are presented. Because of its higher spectral dispersion and the fact that all key reactions directly involve the nitrogen centers,15N NMR provides a much larger amount of detail than do1H and13C NMR spectroscopy. Symmetric and asymmetric dimethylol urea can be clearly distinguished and separated from monomethylol urea, trimethylol urea, and methylene-bridged urea. The existence of hemiformals of methylol urea is confirmed. 1,3,5-Oxadiazinan-4-on (uron) and its derivatives were not found in the reaction mixtures investigated here but were prepared via alternative routes. The molar ratios of formaldehyde to urea were 1, 2, and 4, the pH values 7.5 and 8.5, and the reaction temperature 60 °C. Copyright 2014 John Wiley & Sons, Ltd. 15N-enriched urea is used in combination with quantitative15N and13C NMR spectroscopy and a Virtual Reference. This allows for a detailed peak assignment and absolute quantification of the early steps of this industrial process, which involves a complex reaction network. A detailed peak assignment for all three nuclei, a full quantitative description of the reaction mixture's composition and a model describing changes in shift depending on formaldehyde substitution are given. Copyright