7388-44-5

Basic information

• Product Name: tetrahydro-3,5-bis(methoxymethyl)-4H-1,3,5-oxadiazin-4-one
• Synonyms: tetrahydro-3,5-bis(methoxymethyl)-4H-1,3,5-oxadiazin-4-one;1,3-Bis(methoxymethyl) uron;BIS(METHOXYMETHYL)-(OXYDIMETHYLENE)UREA;4H-1,3,5-Oxadiazin-4-one, tetrahydro-3,5-bis(methoxymethyl)-;Ai3-09491;Bis(methoxymethyl)uron;Dextraset;Dextraset un
• CAS NO: 7388-44-5
• Molecular Formula: C₇H₁₄N₂O₄
• Molecular Weight: 190.19706
• EINECS: 230-970-2
• Mol File: 7388-44-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 295.6°C at 760 mmHg
• Flash Point: 132.6°C
• Appearance: /
• Density: 1.159g/cm³
• Vapor Pressure: 0.00151mmHg at 25°C
• Refractive Index: 1.459
• CAS DataBase Reference: tetrahydro-3,5-bis(methoxymethyl)-4H-1,3,5-oxadiazin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: tetrahydro-3,5-bis(methoxymethyl)-4H-1,3,5-oxadiazin-4-one(7388-44-5)
• EPA Substance Registry System: tetrahydro-3,5-bis(methoxymethyl)-4H-1,3,5-oxadiazin-4-one(7388-44-5)

Safety Data

• Hazardous Substances Data: 7388-44-5(Hazardous Substances Data)

Usage

General Description

Tetrahydro-3,5-bis(methoxymethyl)-4H-1,3,5-oxadiazin-4-one is a chemical compound with the molecular formula C9H16N2O5. It is a heterocyclic compound that contains both nitrogen and oxygen in its ring structure. tetrahydro-3,5-bis(methoxymethyl)-4H-1,3,5-oxadiazin-4-one is often used in the field of medicinal chemistry and pharmaceutical research due to its potential biological activity. It is also used as a precursor in the synthesis of various pharmaceuticals and agrochemicals. Additionally, it has been studied for its potential as a building block in the development of new materials and as a potential synthetic intermediate in organic chemistry.

InChI:InChI=1/C7H14N2O4/c1-11-3-8-5-13-6-9(4-12-2)7(8)10/h3-6H2,1-2H3

Upstream product

• 50-00-0 formaldehyd 
• 1910-86-7 bis-(N'-hydroxymethyl-ureidomethyl)-ether 
• 57-13-6 urea 
• 67-56-1 methanol 
• 2787-01-1 tetra(hydroxymethyl)urea 

Downstream Products

• 22939-30-6 3-hydroxymethyl-1,3,5-oxadiazinan-4-on 
• 542-29-0 1,3,5-oxadiazinan-4-on 
• 7327-69-7 3,5-bis-hydroxymethyl-1,3,5-oxadiazinan-4-on 
• 102894-37-1 3,5-bis-(2-ethoxy-3,5-dimethyl-benzyl)-tetrahydro-[1,3,5]oxadiazin-4-one 
• 36042-69-0 hexa-P-phenyl-P,P'-(4-oxo-[1,3,5]oxadiazinane-3,5-diyldimethyl)-bis-phosphonium; dibromide 
• 102471-03-4 3,5-bis-(2-hydroxy-3,5-dimethyl-benzyl)-tetrahydro-[1,3,5]oxadiazin-4-one 

Relevant articles and documents

Quantitative and qualitative 1H, 13C, and 15N NMR spectroscopic investigation of the urea-formaldehyde resin synthesis

Urea-formaldehyde resins are bulk products of the chemical industry. Their synthesis involves a complex reaction network. The present work contributes to its elucidation by presenting results from detailed NMR spectroscopic studies with different methods. Besides1H NMR and13C NMR, 15N NMR spectroscopy is also applied.15N-enriched urea was used for the investigations. A detailed NMR signal assignment and a model of the reaction network of the hydroxymethylation step of the synthesis are presented. Because of its higher spectral dispersion and the fact that all key reactions directly involve the nitrogen centers,15N NMR provides a much larger amount of detail than do1H and13C NMR spectroscopy. Symmetric and asymmetric dimethylol urea can be clearly distinguished and separated from monomethylol urea, trimethylol urea, and methylene-bridged urea. The existence of hemiformals of methylol urea is confirmed. 1,3,5-Oxadiazinan-4-on (uron) and its derivatives were not found in the reaction mixtures investigated here but were prepared via alternative routes. The molar ratios of formaldehyde to urea were 1, 2, and 4, the pH values 7.5 and 8.5, and the reaction temperature 60 °C. Copyright 2014 John Wiley & Sons, Ltd. 15N-enriched urea is used in combination with quantitative15N and13C NMR spectroscopy and a Virtual Reference. This allows for a detailed peak assignment and absolute quantification of the early steps of this industrial process, which involves a complex reaction network. A detailed peak assignment for all three nuclei, a full quantitative description of the reaction mixture's composition and a model describing changes in shift depending on formaldehyde substitution are given. Copyright