54221-93-1

Usage

Uses

Used in Pharmaceutical Industry:
2,6-Dimethylisonicotinic Acid is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its presence in the pyridine and carboxylic acid families suggests that it may be involved in the development of new drugs or the improvement of existing ones.
Used in Agrochemical Industry:
2,6-Dimethylisonicotinic Acid is used as a building block in the creation of agrochemicals, such as pesticides and herbicides. Its chemical structure may contribute to the effectiveness of these products in controlling pests and weeds in agricultural settings.
Used in Chemical Research:
2,6-Dimethylisonicotinic Acid is used as a research compound in academic and industrial laboratories. Its unique structure may provide insights into the properties and reactions of pyridine and carboxylic acid derivatives, leading to the discovery of new applications and uses.

InChI:InChI=1/C8H9NO2/c1-5-3-7(8(10)11)4-6(2)9-5/h3-4H,1-2H3,(H,10,11)

Upstream product

• 108-75-8 2,4,6-trimethyl-pyridine 
• 18206-06-9 2,6-dimethyl-4-pyridine carboxaldehyde 
• 39965-81-6 2,6-dimethylisonicotinonitrile 
• 13959-27-8 2-(2,6-dimethyl-[4]pyridyl)-propane-1,3-diol 
• 110-86-1 pyridine 
• 7446-08-4 selenium(IV) oxide 
• 1122-43-6 2,6-dimethyl-3-hydroxypyridine 
• 124-38-9 carbon dioxide 
• 3512-80-9 4-amino-2,6-lutidine 
• 1073-23-0 2,6-lutidine N-oxide 
• 87117-15-5 1-methoxy-2,6-dimethylpyridinium methyl sulfate 

Downstream Products

• 142896-15-9 methyl 2,6-dimethylpyridine-4-carboxylate 
• 39965-80-5 4-Ethoxacarbonyl-2,6-dimethyl-pyridin 
• 151427-26-8 2,6-dimethylisonicotinoyl chloride hydrochloride 
• 151427-27-9 N-(4-methoxyphenacyl)-2,6-dimethylisonicotinamide 
• 1352719-30-2 N-methoxy-N,2,6-trimethylisonicotinamide 

Relevant academic research and scientific papers

Nickel-catalyzed carboxylation of aryl and heteroaryl fluorosulfates using carbon dioxide

The development of efficient and practical methods to construct carboxylic acids using CO2 as a C1 synthon is of great importance. Nickel-catalyzed carboxylation of aryl fluorosulfates and heteroaryl fluorosulfates with CO2 is described, affording arene carboxylic acids with good to excellent yields under mild conditions. In addition, a one-pot phenol fluorosulfation/carboxylation is developed.

Photophysics of a series of efficient fluorescent pH probes for dual-emission-wavelength measurements in aqueous solutions

This paper evaluates the 5-aryl-2-pyridyloxazole backbone to engineer donor-acceptor fluorescent pH probes after one- or two-photon absorption. Parent fluorophores, as well as derivatives that can be used to label biomolecules, can be easily obtained in good yields. These molecules exhibit a large one-photon absorption in the near-UV range, and a strong fluorescence emission that covers the whole visible domain. The 5-aryl-2-pyridyloxazole derivatives also possess significant cross sections for two-photon absorption. Upon pyridine protonation, large shifts were observed in the absorption spectra after one- and two-photon excitation, as well as in the emission spectra. This feature was used to measure the pKa of the investigated compounds that range between 2 and 8. In most of the investigated derivatives, the pKa increased upon light excitation and protonation exchanges took place during the lifetime of the excited state, as shown by phase-modulation fluorometry analysis. Several 5-aryl-2-pyridyloxazole derivatives are suggested as efficient probes to reliably measure the pH of aqueous solutions by means of ratiometric methods that are dependent on fluorescence emission.

Novel rare earth metal cryptates which are not very sensitive to the fluorescence quenching

The invention relates to a process for reducing the fluorescence quenching caused by the measuring medium in a fluorescence assay, by introducing into said medium of rare earth metal cryptates which are not very sensitive to this fluorescence quenching, said rare earth metal cryptates comprising at least one pyridine radical which is substituted one or more times or unsubstituted. The invention also relates to novel rare earth metal cryptates which are not very sensitive to the fluorescence quenching caused by the measuring medium.

Not sensitive fluorescence quenching cryptate much new rare earth metal

The invention relates to a process for reducing the fluorescence quenching caused by the measuring medium in a fluorescence assay, by introducing into said medium of rare earth metal cryptates which are not very sensitive to this fluorescence quenching, said rare earth metal cryptates comprising at least one pyridine radical which is substituted one or more times or unsubstituted. The invention also relates to novel rare earth metal cryptates which are not very sensitive to the fluorescence quenching caused by the measuring medium.