54223-77-7Relevant academic research and scientific papers
Design, synthesis and activity evaluation of N-(pyridin-4-yl) salicylamides as antimycobacterial agents
Dian, He,Zhou, De-Bin,Mou, Jian-Ping,Yang, Zhu-Qing,Zhong, Jia,Ding, Xiao-Quan,Li, Chong,Wang, Xiao-Hong,Zhang, Jian-Gang
, p. 7269 - 7275 (2014)
A series of N-(pyridin-4-yl) salicylamides derivatives were prepared through acylation of the corresponding acetylsalicyloyl chlorides with substituted 4-amino-pyridines. These compounds were evaluated in vitro for antimycobacterial activities against Myc
SYNTHETIC MYCOTOXIN ADSORBENTS AND METHODS OF MAKING AND UTILIZING THE SAME
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, (2022/01/03)
The present invention relates generally to molecularly imprinted polymers (MIPs). In particular, the present invention relates to reusable, ecologically friendly MIPs that can be produced in relatively large quantities, methods of producing the same, and
Development of 5-nitrothiazole derivatives: Identification of leads against both replicative and latent Mycobacterium tuberculosis
Jeankumar, Variam Ullas,Chandran, Manoj,Samala, Ganesh,Alvala, Mallika,Koushik, Pulla Venkat,Yogeeswari, Perumal,Salina, Elena G.,Sriram, Dharmarajan
, p. 7414 - 7417 (2013/02/22)
Twenty eight 5-nitrothiazole derivatives were synthesized and evaluated for in vitro activities against Mycobacterium tuberculosis (MTB), cytotoxicity against HEK 293T. Among the compounds, 5-nitro-N-(5-nitrothiazol-2-yl)furan-2- carboxamide (20) was found to be the most active compound in vitro with MICs of 5.48 μM against log-phase culture of MTB and also non-toxic up to 100 μM.
Cobalt-Catalyzed Epoxidation of Olefins. Dual Pathways for Oxygen Atom Transfer
Koola, J. D.,Kochi, J. K.
, p. 4545 - 4553 (2007/10/02)
Cobalt catalysis of olefin oxidation with tert-butyl hydroperoxide and iodosylbenzene as terminal oxidants is examined with CoII(Ia), where the ligand Ia is the bis-salicylamide dianion 2,3-bis(3,5-dichloro-2-oxybenzamido)-2,3-dimethylbutane.The catalytic epoxidation of norbornene with tert-butyl hydroperoxide and with iodosulbenzene proceeds via different pathways, since the former is effectively inhibited by ionol (2,6-di-tert-butyl-p-cresol) whereas the latter is not.A radical chain mechanism is proposed for tert-butyl hydroperoxide in which the homolytic addition of tert-butylperoxy radicals to the double bond leads to epoxidation.Cobalt catalysis is associated with the CoII/CoIII interconversion in the one-electron redox processes mediating the formation of the critical tert-butylperoxy radical.By contrast, there is no evidence for radical intermediates in the cobalt catalysis with iodosylbenzene which occurs readily with various types of olefins including 2-hexene, cyclooctene, β-methylstyrene, and even cyclohexene.A two-electron mechanism is proposed to account for the high reactivity, selectivity, and stereochemical retention in the catalytic epoxidation, despite the low solubility of CoII(Ia) in the reaction aspects of the cobalt-catalyzed epoxidations with iodosylbenzene.
The Design of Multianionic Chelating Ligands for the Production of Inorganic Oxidizing Agents. Osmium Coordination Chemistry That Provides Stable Potent Oxidizing Agents and Stable Potent Reducing Agents
Anson, Fred C.,Christie, Judith A.,Collins, Terrence J.,Coots, Robert J.,Furutani, Tracy T.,et al.
, p. 4460 - 4472 (2007/10/02)
The design of multianionic chelating ligands for use in producing new oxidizing agents is discussed.Two potentially tetradentate tetraanionic ligands, 1,2-bis(3,5-dichloro-2-hydroxybenzamido)ethane (H4CHBA-Et (1)) and 1,2-bis(3,5-dichloro-2-hydroxybenzami
