5423-67-6

Basic information

• Product Name: 3-Hydroxy-1,2,3,4-tetrahydrobenzo[h]quinoline
• Synonyms: 3-Hydroxy1,2,3,4 tetrahydrobenzo H quinolin3ol;3-HYDROXY-1,2,3,4-TETRAHYDROBENZO[H]QUINOLINE;1,2,3,4-Tetrahydrobenzo[h]quinolin-3-ol
• CAS NO: 5423-67-6
• Molecular Formula: C₁₃H₁₃NO
• Molecular Weight: 199.25
• EINECS: 226-556-6
• Product Categories: pharmacetical
• Mol File: 5423-67-6.mol
• Article Data: 2

Chemical Properties

• Melting Point: 148-150 °C
• Boiling Point: 424.3°C at 760mmHg
• Flash Point: 210.5°C
• Appearance: /
• Density: 1.219g/cm³
• Vapor Pressure: 5.87E-08mmHg at 25°C
• Refractive Index: 1.672
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 14.33±0.20(Predicted)
• CAS DataBase Reference: 3-Hydroxy-1,2,3,4-tetrahydrobenzo[h]quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Hydroxy-1,2,3,4-tetrahydrobenzo[h]quinoline(5423-67-6)
• EPA Substance Registry System: 3-Hydroxy-1,2,3,4-tetrahydrobenzo[h]quinoline(5423-67-6)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 5423-67-6(Hazardous Substances Data)

Usage

Chemical Properties

White solid

InChI:InChI=1/C13H13NO/c15-11-7-10-6-5-9-3-1-2-4-12(9)13(10)14-8-11/h1-6,11,14-15H,7-8H2/t11-/m1/s1

Upstream product

• 134-32-7 1-amino-naphthalene 
• 106-89-8 epichlorohydrin 
• 230-27-3 7,8-benzoquinoline 

Downstream Products

• 230-27-3 7,8-benzoquinoline 
• 233-34-1 1H-benz[g]indole 
• 102159-96-6 benzoic acid benzo[h]quinolin-3-yl ester 
• 5223-80-3 1,2,3,4-tetrahydrobenzo[h]quinoline 
• 30426-97-2 6-Chlor-benzochinolin 

Relevant articles and documents

Synthesis and structures of 3-hydroxy-6-(R-phenylazo)-7,8-benzo-1,2,3,4- tetrahydroquinolines as products of analytical test reactions for nitrite and nitrate anions

An improved procedure was proposed for the synthesis of 3-hydroxy-7,8-benzo-1,2,3,4-tetrahydroquinoline, which is used as a reagent for the analytical test reaction for nitrate and nitrite anions based on azo coupling with diazo compounds. 3-Hydroxy-6-(R-phenylazo)-7,8-benzo-1,2,3,4- tetrahydroquinolines (R = 2-COOH, 4-COOH, or 4-SO3H) were synthesized by azo coupling reactions in 65-70% yields. The structures of these compounds were confirmed by elemental analysis, 1H NMR and IR spectroscopy, and X-ray diffraction. Based on the X-ray data, the bathochromic shift in the UV spectrum of the o-carboxy isomer compared to the p-carboxy isomer (Δλmax = 50 nm) is attributed to a strong intramolecular hydrogen bond.