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N-(3-chloro-2-methylphenyl)-2-({5-[(3-methylphenyl)amino]-1,3,4-thiadiazol-2-yl}sulfanyl)acetamide is a complex organic compound with a molecular formula of C16H15ClN4OS3. It is characterized by a 3-chloro-2-methylphenyl group attached to an acetamide moiety, which in turn is connected to a 1,3,4-thiadiazol-2-ylsulfanyl group. This thiadiazole ring is further substituted with a 3-methylphenyl group and an amino group. The compound is known for its potential applications in pharmaceuticals, particularly as an intermediate in the synthesis of various therapeutic agents. Its structure provides a unique combination of functional groups that can contribute to its biological activity, making it a subject of interest in medicinal chemistry research.

5427-42-9

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5427-42-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 5427-42-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,2 and 7 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 5427-42:
(6*5)+(5*4)+(4*2)+(3*7)+(2*4)+(1*2)=89
89 % 10 = 9
So 5427-42-9 is a valid CAS Registry Number.

5427-42-9Downstream Products

5427-42-9Relevant academic research and scientific papers

Synthesis and in vitro antitubercular activity of a series of quinoline derivatives

de Souza, Marcus V.N.,Pais, Karla C.,Kaiser, Carlos R.,Peralta, Monica A.,de L. Ferreira, Marcelle,Lourenco, Maria C.S.

experimental part, p. 1474 - 1480 (2009/08/15)

A series of 33 quinoline derivatives have been synthesized and evaluated for their in vitro antibacterial activity against Mycobacterium tuberculosis H37Rv using the Alamar Blue susceptibility test and the activity expressed as the minimum inhibitory concentration (MIC) in μg/mL. Compounds 5e and 5f exhibited a significant activity at 6.25 and 3.12 μg/mL, respectively, when compared with first line drugs such as ethambutol and could be a good starting point to develop new lead compounds in the fight against multi-drug resistant tuberculosis.

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