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5428-89-7

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5428-89-7 Usage

Uses

5-Chloropyrimidin-2-amine is an useful reagent of research interest in the preparation of JAK2 inhibitors for the treatment of myeloproliferative disorders and SIRT2 inhibitors for the treatment of Huntington''s disease.

Synthesis Reference(s)

Journal of the American Chemical Society, 64, p. 567, 1942 DOI: 10.1021/ja01255a030

Check Digit Verification of cas no

The CAS Registry Mumber 5428-89-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,2 and 8 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 5428-89:
(6*5)+(5*4)+(4*2)+(3*8)+(2*8)+(1*9)=107
107 % 10 = 7
So 5428-89-7 is a valid CAS Registry Number.
InChI:InChI=1/C4H4ClN3/c5-3-1-7-4(6)8-2-3/h1-2H,(H2,6,7,8)

5428-89-7 Well-known Company Product Price

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  • (Code)Product description
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  • Alfa Aesar

  • (L19248)  2-Amino-5-chloropyrimidine, 97%   

  • 5428-89-7

  • 250mg

  • 213.0CNY

  • Detail
  • Alfa Aesar

  • (L19248)  2-Amino-5-chloropyrimidine, 97%   

  • 5428-89-7

  • 1g

  • 584.0CNY

  • Detail
  • Alfa Aesar

  • (L19248)  2-Amino-5-chloropyrimidine, 97%   

  • 5428-89-7

  • 5g

  • 2326.0CNY

  • Detail
  • Aldrich

  • (651567)  2-Amino-5-chloropyrimidine  97%

  • 5428-89-7

  • 651567-1G

  • 872.82CNY

  • Detail
  • Aldrich

  • (651567)  2-Amino-5-chloropyrimidine  97%

  • 5428-89-7

  • 651567-5G

  • 1,571.31CNY

  • Detail

5428-89-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Amino-5-chloropyrimidine

1.2 Other means of identification

Product number -
Other names 5-Chloropyrimidin-2-amine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5428-89-7 SDS

5428-89-7Relevant articles and documents

Hultquist bei Roblin,Winnek,English

, p. 570 (1942)

N-Chloro-N-methoxybenzenesulfonamide: A Chlorinating Reagent

Pu, Xiaoqiu,Li, Qingwei,Lu, Zehai,Yang, Xianjin

supporting information, p. 5937 - 5940 (2016/12/26)

A structurally simple and reactive chlorinating reagent, N-chloro-N-methoxybenzenesulfonamide, was conveniently and economically prepared in high yield. 1,3-Diketones, β-keto esters, benzoyl trifluoroacetones, phenols, anisoles, heteroarenes, and aromatic amines were successfully chlorinated, and the products were obtained in good to high yields.

HETEROAROMATIC AMIDES AS INHIBITOR OF FACTOR XA

-

, (2008/06/13)

This application relates to heteroaromatic amides (or a pharmaceutically acceptable salt thereof) as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa, as well as a process for its preparation and intermediates therefor.

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