54286-62-3 Usage
General Description
2,1,3-Benzoxadiazole-5-carbonitrile is a chemical compound with the molecular formula C8H3N3O. It is a heterocyclic compound that contains a benzene ring fused to a 1,2,5-oxadiazole ring. The presence of a cyano group (CN) at the 5-position of the oxadiazole ring gives the compound its carbonitrile suffix. 2,1,3-Benzoxadiazole-5-carbonitrile has potential applications in the field of organic synthesis and pharmaceuticals due to its unique structural and chemical properties. It has been studied for its potential use as a fluorescent probe and in the development of novel organic semiconductors. Additionally, its derivatives have shown promising biological activities, making it an interesting compound for further research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 54286-62-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,2,8 and 6 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 54286-62:
(7*5)+(6*4)+(5*2)+(4*8)+(3*6)+(2*6)+(1*2)=133
133 % 10 = 3
So 54286-62-3 is a valid CAS Registry Number.
InChI:InChI=1/C7H3N3O/c8-4-5-1-2-6-7(3-5)10-11-9-6/h1-3H
54286-62-3Relevant articles and documents
Synthesis of carboxyimidamide-substituted benzo[c][1,2,5]oxadiazoles and their analogs, and evaluation of biological activity against Leishmania donovani
Keurulainen, Leena,Heiskari, Mikko,Nenonen, Satu,Nasereddin, Abedelmajeed,Kopelyanskiy, Dmitry,Leino, Teppo O.,Yli-Kauhaluoma, Jari,Jaffe, Charles L.,Kiuru, Paula
, p. 1673 - 1678 (2015/09/15)
A facile synthesis route to carboxyimidamide-substituted benzoxadiazoles and related derivatives was developed. A total of 25 derivatives were synthesized. They were evaluated for antileishmanial activity by inhibition of Leishmania donovani axenic amastigote growth using a fluorescent viability microplate assay. The most promising derivative (14) demonstrated an antileishmanial EC50 of 4.0 μM, and it also showed activity in infected macrophages (EC50 5.92 μM) without signs of cytotoxicity.
