54286-62-3 Usage
Uses
Used in Organic Synthesis:
2,1,3-Benzoxadiazole-5-carbonitrile is used as a building block in organic synthesis for the creation of various chemical compounds due to its unique structural and chemical properties.
Used in Pharmaceutical Development:
It is used as a scaffold in the development of new pharmaceuticals, leveraging its potential biological activities and the ability to modify its structure for specific therapeutic effects.
Used in Fluorescent Probes:
2,1,3-Benzoxadiazole-5-carbonitrile is used as a fluorescent probe in research, taking advantage of its optical properties to track and visualize biological processes.
Used in Organic Semiconductors:
2,1,3-Benzoxadiazole-5-carbonitrile is used in the development of novel organic semiconductors, where its electronic properties can contribute to the performance of electronic devices and materials.
Used in Research and Development:
2,1,3-Benzoxadiazole-5-carbonitrile is used as a subject of research for further exploration of its potential applications and properties, including its biological activities and its role in creating new materials and compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 54286-62-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,2,8 and 6 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 54286-62:
(7*5)+(6*4)+(5*2)+(4*8)+(3*6)+(2*6)+(1*2)=133
133 % 10 = 3
So 54286-62-3 is a valid CAS Registry Number.
InChI:InChI=1/C7H3N3O/c8-4-5-1-2-6-7(3-5)10-11-9-6/h1-3H
54286-62-3Relevant academic research and scientific papers
Synthesis of carboxyimidamide-substituted benzo[c][1,2,5]oxadiazoles and their analogs, and evaluation of biological activity against Leishmania donovani
Keurulainen, Leena,Heiskari, Mikko,Nenonen, Satu,Nasereddin, Abedelmajeed,Kopelyanskiy, Dmitry,Leino, Teppo O.,Yli-Kauhaluoma, Jari,Jaffe, Charles L.,Kiuru, Paula
, p. 1673 - 1678 (2015/09/15)
A facile synthesis route to carboxyimidamide-substituted benzoxadiazoles and related derivatives was developed. A total of 25 derivatives were synthesized. They were evaluated for antileishmanial activity by inhibition of Leishmania donovani axenic amastigote growth using a fluorescent viability microplate assay. The most promising derivative (14) demonstrated an antileishmanial EC50 of 4.0 μM, and it also showed activity in infected macrophages (EC50 5.92 μM) without signs of cytotoxicity.
1, 2 DISUBSTITUTED HETEROCYCLIC COMPOUNDS
-
, (2010/01/30)
1,2-disubstituted heterocyclic compounds which are inhibitors of phosphodiesterase 10 are described. Also described are processes, pharmaceutical compositions, pharmaceutical preparations and pharmaceutical use of the compounds in the treatment of mammals, including human(s) for central nervous system (CNS) disorders and other disorders which may affect CNS function. Among the disorders which may be treated are neurological, neurodegenerative and psychiatric disorders including, but not limited to, those associated with cognitive deficits or schizophrenic symptoms.
