54307-83-4Relevant academic research and scientific papers
Primary-amine-catalyzed enantioselective intramolecular aldolizations
Zhou, Jian,Wakchaure, Vijay,Kraft, Philip,List, Benjamin
supporting information; scheme or table, p. 7656 - 7658 (2009/04/10)
Aldol cyclodehydration of 4-substituted-2,6-heptanediones leads to enantiomerically enriched 5-substituted-3-methyl-2-cyclohexene-1-ones, which serve as perfume ingredients and valuable synthetic building blocks.Primary amines derived from cinchona alkalo
Enantiodivergent syntheses of (R)- and (S)- 3,5-dimethylcyclohex-2-en-1- ones from (R)-pulegone
Nangia,Prasuna
, p. 1989 - 1998 (2007/10/02)
R-(+)-pulegone (1) is transformed to (R)-5-methyl-2- (phenylsulfinyl)cyclohexanone (5) (65%, 3 steps). Sulfoxide 5 is converted to R-(-)-3,5-dimethylcyclohex-2-en-1-one (4) (53%, 4 steps) and S-(+)-4 (26%, 3 steps).
Enantiomerically pure vinylketene acetals in the Diels-Alder reaction. Catalysis and facial selectivity
Boehler,Konopelski
, p. 4519 - 4538 (2007/10/02)
A series of enantiomerically pure vinylketene acetals which function as diastereoselective dienes in the Diels-Alder reaction have been developed. Most selective are (4R, 5R)-4,5-diphenyl-2-(2-methyl-2-propenidene)-1,3-dioxolane (8) and (4R, 5R)-4,5-diphe
Enantioselective cyclizations of acyclic 1,5-diketones
Agami, Claude,Platzer, Nicole,Sevestre, Hubert
, p. 358 - 360 (2007/10/02)
4-Methyl-2,6-heptanedione 1 was cyclized to enone (-)-4 via a (S)-proline-catalyzed intramolecular aldol reaction followed by dehydration.Replacement of the 4-methyl group by either an iso-propyl or a tert-butyl subtituent leads to a dramatic lowering of
