54316-25-5Relevant academic research and scientific papers
Ruthenium-catalyzed formation of pyrazoles or 3-hydroxynitriles from propargyl alcohols and hydrazines
Kaufmann, Julia,J?ckel, Elisabeth,Haak, Edgar
supporting information, p. 91 - 101 (2019/07/09)
Functionalized pyrazoles are generated from secondary propragyl alcohols and hydrazines in a ruthenium-catalyzed cascade process, consisting of redox isomerization, Michael addition, cyclocondensation and dehydrogenation steps. The same bifunctional catalyst mediates the conversion of tertiary propargyl alcohols with hydrazine to 3-hydroxynitriles via anti-Markovnikov hydroamination followed by elimination of ammonia.
SYNTHESIS, ELECTRONIC STRUCTURE, AND PHYSICOCHEMICAL CHARACTERISTICS OF PYRAZOLOPYRIDAZINIUM
Voshula, V. N.,Vysotskii, Yu. B.,Seraya, V. I.,Novikova, N. T.,Mushii, R. Ya.,Dulenko, V. I.
, p. 1349 - 1357 (2007/10/02)
The interaction of 1-methallylpyrazoles with acetic or propionic anhydride in the presence of perchloric acid forms products of acylation at the double bond and subsequent heterocyclization - pyrazolopyridazinium salts - that are representatives of a new heteroaromatic system.Analogous cyclization is observed in the acylation of 3-(2-hydroxy-2-methylpropyl)pyrazole.
