54337-10-9Relevant academic research and scientific papers
Novel [ONN] tridentate fourth subgroup metal complex as well as preparation method and application thereof
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Paragraph 0094; 0096, (2020/06/16)
The invention provides a novel [ONN] tridentate fourth subgroup metal complex and a preparation method and application thereof. The novel [ONN] tridentate fourth subgroup metal complex has a structureas shown in formula I which is described in the specifi
Expeditious Synthesis of Multisubstituted Quinolinone Derivatives Based on Ring Recombination Strategy
Yokoo, Kazuma,Mori, Keiji
, p. 244 - 248 (2019/12/30)
We achieved a concise construction of 3-substituted quinolinone derivatives based on a ring recombination strategy. In this process, seven transformations involving two types of cyclization proceeded in one pot to afford various quinolinone derivatives in good to excellent chemical yields (up to 98%).
Spirocyclic Tetramates by Sequential Knoevenagel and [1,5]-Prototropic Shift
Josa-Culleré, Laia,Hirst, Michael G.,Lockett, Jonathan P.,Thompson, Amber L.,Moloney, Mark G.
, p. 9671 - 9683 (2019/09/06)
Highly functionalized spirocyclic tetramates were prepared via a sequential Knoevenagel reaction and [1,5]-prototropic shift (T-reaction) of bicyclic tetramates. While these compounds isomerize in solution, stable analogues can be prepared via an appropri
Directed Amination of Aryl Methyl Ethers Mediated by Ti(NMe2)4 at Room Temperature
Chen, Zhou,Liu, Jinna,Pei, Hao,Liu, Wei,Chen, Yanmei,Wu, Jian,Li, Wu,Li, Yahong
supporting information, p. 3406 - 3409 (2015/07/28)
An efficient C-O amination of aryl methyl ethers has been achieved. This transformation proceeds via imine-directed Ti(IV)-mediated cross-coupling reactions between aryl methyl ethers and Ti(NR2)4 at room temperature, straightforwardly leading to a series of arylamines. This protocol features a wide substrate scope, exclusive regioselectivity, and mild reaction conditions.
O-Hydroxyl- or o-amino benzylamine-tacrine hybrids: Multifunctional biometals chelators, antioxidants, and inhibitors of cholinesterase activity and amyloid-β aggregation
Mao, Fei,Huang, Ling,Luo, Zonghua,Liu, Anqiu,Lu, Chuanjun,Xie, Zhiyong,Li, Xingshu
, p. 5884 - 5892 (2012/11/06)
In an effort to identify novel multifunctional drug candidates for the treatment of Alzheimer's disease (AD), a series of hybrid molecules were synthesised by reacting N-(aminoalkyl)tacrine with salicylic aldehyde or derivatives of 2-aminobenzaldehyde. Th
Selective activation of enantiotopic C(sp3)-hydrogen by means of chiral phosphoric acid: Asymmetric synthesis of tetrahydroquinoline derivatives
Mori, Keiji,Ehara, Kensuke,Kurihara, Kazuki,Akiyama, Takahiko
supporting information; experimental part, p. 6166 - 6169 (2011/06/21)
Chiral phosphoric acid-catalyzed asymmetric C-H functionalization has been achieved. In this process, enantiotopic C(sp3)-hydrogen is selectively activated by chiral phosphoric acid to afford tetrahydroquinoline derivatives with excellent enantioselectivities (up to 97% ee).
Product-selectivity control by the nature of the catalyst: Lewis acid-catalyzed selective formation of ring-fused tetrahydroquinolines and tetrahydroazepines via intramolecular redox reaction
Zhou, Guanghua,Zhang, Junliang
supporting information; scheme or table, p. 6593 - 6595 (2010/10/21)
Selective synthesis of ring-fused tetrahydroquinolines and tetrahydroazepines from the same starting materials was achieved by subtle use of the oxophilic Sc(OTf)3 or carbophilic IPrAuOTf as the catalyst.
Aluminum complexes with bidentate N,N-dialkylaniline-arylamido ligands: Synthesis, structures, and catalytic properties for efficient ring-opening polymerization of ε-caprolactone
Gao, Aihong,Mu, Ying,Zhang, Jingshun,Yao, Wei
experimental part, p. 3613 - 3621 (2009/12/08)
A number of Al complexes bearing bidentate N,N-dialkylaniline-arylamido ligands, OrMo-(ArNCH2)C6H4NR 2AlMe2 (R = Me, Ar = 2,6-iPr2C 6H3, 3a; 2,6-Et2C6
Benzimidazoles, their production, formulation and use as gastric acid secretion inhibitors
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, (2008/06/13)
There are described compounds of formula I, in which R1 to R8 have a variety of significances, including alkoxy, hydrogen, alkyl, n is 0 or l, R11 is hydrogen, phenyl, alkenyl, or alkyl optionally substituted by
