54337-90-5

Usage

Uses

Used in Pharmaceutical Industry:
3,4-Dihydroxybenzamide is used as an intermediate in the synthesis of pharmaceuticals for its potential therapeutic applications. Its antioxidant and anti-inflammatory properties are being studied for their potential benefits in treating various conditions.
Used in Agrochemical Industry:
In the agrochemical sector, 3,4-Dihydroxybenzamide serves as an intermediate in the synthesis of agrochemicals, contributing to the development of products that can enhance crop protection and yield.
Used in Organic Synthesis:
3,4-Dihydroxybenzamide is utilized as a building block in organic synthesis due to its reactivity, enabling the creation of a wide range of chemical compounds for various applications.
Used in the Synthesis of Bioactive Compounds:
3,4-DIHYDROXYBENZAMIDE is also used in the synthesis of various bioactive compounds, highlighting its importance in the development of new molecules with potential biological activities.

InChI:InChI=1/C7H7NO3/c8-7(11)4-1-2-5(9)6(10)3-4/h1-3,9-10H,(H2,8,11)

Upstream product

• 112057-04-2 2-oxo-benzo[1,3]dioxole-5-carbonyl chloride 
• 95946-91-1 3,4-dibenzyloxybenzamide 
• 7664-41-7 ammonia 
• 17345-61-8 3,4-dihydroxybenzonitrile 
• 94-53-1 Piperonylic acid 
• 5447-02-9 3,4-dibenzyloxybenzaldehyde 
• 1570-05-4 3,4-bis(benzyloxy)benzoic acid 
• 75-52-5 nitromethane 
• 120-80-9 benzene-1,2-diol 
• 139-85-5 3,4-dihydroxybenzaldehyde 

Relevant academic research and scientific papers

Nitromethane in polyphosphoric acid- A new reagent for carboxyamidation and carboxylation of activated aromatic compou

A new method of carboxyamidation of aromatic compounds based on their reaction with nitromethane in polyphosphoric acid has been developed. Upon the hydrolysis of benzamides during the reaction mixture workup, the corresponding benzoic acids can be obtained. Taylor & Francis Group, LLC.

A mild and expeditious synthesis of amides from aldehydes using bio glycerol-based carbon as a recyclable catalyst

The new bioglycerol-based carbon catalyst acts as an efficient, readily available, and reusable catalyst for the synthesis of amides, when aldehyde and hydroxylamine hydrochloride react in acetonitrile.

PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS

The invention relates to a process for straightening keratin fibres, comprising: (i) a step in which a straightening composition containing at least two denaturing agents is applied to the keratin fibres, (ii) a step in which the temperature of the keratin fibres is raised, using a heating means, to a temperature of between 110 and 250° C.

Effects of electron-withdrawing substituents on DPPH radical scavenging reactions of protocatechuic acid and its analogues in alcoholic solvents

The DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging activity of protocatechuic acid (3,4-dihydroxybenzoic acid) and its related catechols was examined. Compounds possessing strong electron-withdrawing substituents showed high activity. NMR analysis of the reaction mixtures of catechols and DPPH radical in methanol showed the formation of methanol adducts. The results suggest that high radical scavenging activity of catechols in alcohol is due to a nucleophilic addition of an alcohol molecule on o-quinones, which leads to a regeneration of a catechol structure. Furthermore, the radical scavenging activity in alcohols would largely depend on the electron-withdrawing/donating substituents, since they affect the susceptibility toward nucleophilic attacks on o-quinone.

Hydroxybenzohydroxamic acids, benzamides and esters and related compounds as ribonucleotide reductase inhibitors

Di, tri and tetrahydroxybenzohydroxamic acids, amides and the corresponding di, tri and tetrahydroxy substituted phenylalkanohydroxamic acids, amides and phenyl esters, ribonucleotide reductase inhibitors.

Hydroxybenzohydroxamic acids, benzamides and esters as ribonucleotide reductase inhibitors

Di and trihydroxybenzohydroxamic acids, amides, alkyl substituted amides and phenyl esters, ribonucleotide reductase inhibitors.