54367-97-4

Basic information

• Product Name: Cyclohexanone, 2-(2-naphthalenyl)-
• CAS NO: 54367-97-4
• Molecular Formula: C16H16O
• Molecular Weight: 224.302
• Mol File: 54367-97-4.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Cyclohexanone, 2-(2-naphthalenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanone, 2-(2-naphthalenyl)-(54367-97-4)
• EPA Substance Registry System: Cyclohexanone, 2-(2-naphthalenyl)-(54367-97-4)

Safety Data

• Hazardous Substances Data: 54367-97-4(Hazardous Substances Data)

Upstream product

• 580-13-2 2-bromonaphthalene 
• 6651-36-1 1-(Trimethylsilyloxy)cyclohexene 
• 32316-92-0 naphthalene-2-boronic acid 
• 822-87-7 2-Chlorocyclohexanone 
• 612-55-5 2-iodonaphthalene 
• 108-94-1 cyclohexanone 
• 70080-13-6 2-naphthylacetaldehyde 
• 838826-68-9 2-(2-oxo-5-hexenyl)naphthalene 
• 377776-09-5 2-naphthalen-2-yl-cyclohexanol 
• 90-11-9 1-Bromonaphthalene 
• 21473-01-8 2-naphthalenylmagnesium bromide 
• 54607-03-3 2-(cyclohex-1-en-1-yl)naphthalene 

Downstream Products

• 167476-36-0 2-naphthyl-1-(trimethylsilyloxy)cyclohex-1-ene 
• 132104-10-0 6-(naphthalen-2-yl)-6-oxohexanoic acid 
• 179601-92-4 (1S,2R)-(-)-2-(naphthalen-2-yl)-cyclohexanol 
• 179601-87-7 (1R,2S)-(-)-2-(naphthalen-2-yl)-cyclohexanol 

Relevant articles and documents

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Direct Asymmetric α-Hydroxylation of Cyclic α-Branched Ketones through Enol Catalysis

Enantiopure α-hydroxy carbonyl compounds are common scaffolds in natural products and pharmaceuticals. Although indirect approaches towards their synthesis are known, direct asymmetric methodologies are scarce. Herein, we report the first direct asymmetric α-hydroxylation of α-branched ketones through enol catalysis, enabling a facile access to valuable α-keto tertiary alcohols. The transformation, characterized by the use of nitrosobenzene as the oxidant and a new chiral phosphoric acid as the catalyst, delivers a good scope and excellent enantioselectivities.

p-Toluenesulfonic acid catalysed fluorination of α-branched ketones for the construction of fluorinated quaternary carbon centres

A p-toluenesulfonic acid catalyzed fluorination of α-branched ketones for the construction of fluorinated quaternary carbon centers has been developed, featuring a broad substrate scope, environmentally benign reaction conditions, and operational simplicity.