543690-31-9

Upstream product

• 357278-33-2 Benzyl-{(R)-1-[(2R,3S)-3-(tert-butyl-diphenyl-silanyloxymethyl)-oxiranyl]-allyl}-amine 
• 80379-05-1 but-3-en-1-yl triflate 
• 543690-30-8 (2R,3R,4R)-4-Benzylamino-hex-5-ene-1,2,3-triol 

Downstream Products

• 543690-33-1 (1R,2R)-1-[(2R)-1-benzyl-1,2,5,6-tetrahydropyridin-2-yl]propane-1,2,3-triol 
• 125279-72-3 (1R,2R,8aR)-lentiginosine 

Relevant academic research and scientific papers

Concise asymmetric syntheses of (-)-lentiginosine and of its pyrrolizidinic analogue.

(-)-Lentiginosine and its pyrrolizidinic analogue have been prepared in a straightforward five-step sequence from a versatile chiral cis-alpha,beta-epoxyamine.

Asymmetric syntheses of (-)-lentiginosine and an original pyrrolizidinic analogue thereof from a versatile epoxyamine intermediate

Ready access to natural (-)-lentiginosine and its pyrrolizidinic analogue from a chiral vinylic epoxyamine in a straightforward five-step sequence is presented. Careful use of the RCM reaction on aminotriols 5 and 6 constitutes the key feature of the synt