543740-86-9 Usage
Derivative of phenylamine
A compound that is structurally related to phenylamine, which is a basic building block in organic chemistry.
Contains bromine and ethynyl groups
The presence of bromine atoms adds reactivity and unique properties to the compound, while the ethynyl group (C≡C) provides a carbon-carbon triple bond that can be used in further chemical reactions.
Potential applications in organic synthesis
The compound can be used as a starting material or intermediate in the synthesis of more complex organic molecules.
Potential applications in pharmaceutical research
Due to its unique structure and reactivity, 2,4-dibromo-6-ethynyl-phenylamine may be used to develop new drugs or improve existing ones.
Use in the development of new materials
The compound's properties may be harnessed to create new materials with unique characteristics for various applications.
Building block for more complex organic molecules
The compound can be used as a precursor to create larger, more complex organic molecules with diverse applications.
Since the properties and potential hazards of 2,4-dibromo-6-ethynyl-phenylamine are not fully known, it is important to follow safety guidelines and precautions when working with this chemical.
Check Digit Verification of cas no
The CAS Registry Mumber 543740-86-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,4,3,7,4 and 0 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 543740-86:
(8*5)+(7*4)+(6*3)+(5*7)+(4*4)+(3*0)+(2*8)+(1*6)=159
159 % 10 = 9
So 543740-86-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H5Br2N/c1-2-5-3-6(9)4-7(10)8(5)11/h1,3-4H,11H2
543740-86-9Relevant articles and documents
Revisiting the Gold-Catalyzed Dimerization of 2-Ethynylanilines: A Room-Temperature and Silver-Free Protocol for the Synthesis of Multifunctional Quinolines
Praveen, Chandrasekar,Perumal
, p. 855 - 864 (2016/03/15)
A room temperature and silver-free protocol for the formation of quinolines from 2-ethynylanilines through a dimerization event was achieved using a dinuclear gold catalyst, Au2(BIPHEP)(NTf2)2. The reaction is inherently modular, allowing for the incorporation of peripheral substituents at any site of the quinoline product. The reaction is readily applied to other heterocyles also as exemplified by the preparation of naphthyridines. Competition reactions to determine the reactivity of dissimilar alkynes demonstrated that the product ratio of dimerization vs intermolecular addition is rather dependent on the electronic nature of aryl substituent on the alkynes. However, control experiments with substrates possessing internal alkynes resulted in cycloisomerization instead of expected dimerization, which is indicative of possible steric influence of the alkyne terminus in the reaction outcome.
