54399-24-5Relevant academic research and scientific papers
N-(phenylselenomethyl)phthalimide as new reagent for mild protection of alcohols as Pim-ethers
Temperini, Andrea,Minuti, Lucio
experimental part, p. 2709 - 2711 (2012/07/16)
A mild activation of N-(phenylselenomethyl)phthalimide by iodonium ion in the presence of alcohols to give the corresponding O-phthalimidomethyl derivatives (Pim-ethers) is provided. Simple cleavage of the phthalimido group with ethylenediamine is also reported thus making this approach a new and efficient method of protecting alcohols.
Phthalimidomethylation of O-nucleophiles with O-phthalimidomethyl trichloroacetimidate: A powerful imidomethylating agent for O-protection
Ali, Ibrahim A. I.,Abdel-Rahman, Adel A.-H.,El Ashry, El Sayed H.,Schmidt, Richard R.
, p. 1065 - 1070 (2007/10/03)
Phthalimidomethylation of oxygen nucleophiles by using O-phthalimidomethyl (Pim) trichloroacetimidate in the presence of TMSOTf has been achieved in high yields. Hydrazinolysis of the phthalimido group from the O-derivatives leads to the hydroxy precursor
