544-57-0

Basic information

• Product Name: 2-HYDROXYTETRACOSANOIC ACID
• Synonyms: CEREBRONIC ACID;2-HYDROXYTETRACOSANOIC ACID;2-HYDROXY C24:0 ACID;2-Hydroxylignoceric acid
• CAS NO: 544-57-0
• Molecular Formula: C₂₄H₄₈O₃
• Molecular Weight: 384.64
• Mol File: 544-57-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 508.8 °C at 760 mmHg
• Flash Point: 275.6 °C
• Appearance: /
• Density: 0.921 g/cm³
• Vapor Pressure: 1.75E-12mmHg at 25°C
• Refractive Index: 1.469
• CAS DataBase Reference: 2-HYDROXYTETRACOSANOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-HYDROXYTETRACOSANOIC ACID(544-57-0)
• EPA Substance Registry System: 2-HYDROXYTETRACOSANOIC ACID(544-57-0)

Safety Data

• Hazardous Substances Data: 544-57-0(Hazardous Substances Data)

Usage

Definition

ChEBI: A very long-chain hydroxy fatty acid composed of lignoceric acid having a 2-hydroxy substituent.

InChI:InChI=1/C24H48O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23(25)24(26)27/h23,25H,2-22H2,1H3,(H,26,27)

Upstream product

• 557-59-5 n-tetracosanoic acid 
• 64-17-5 ethanol 
• 95746-76-2 2-hydroxy-tetracos-15-enoic acid 
• 102809-35-8 (+/-)-2-bromotetracosanoic acid 

Downstream Products

• 557-59-5 n-tetracosanoic acid 
• 2433-96-7 tricosanoic acid 
• 2433-97-8 tricosanoic acid methyl ester 
• 405167-19-3 2-acetoxy-tetracosanoic acid pentafluorophenyl ester 

Relevant articles and documents

Synthesis and absolute configuration of 6-hydroxylated new ceramides in human skin, ceramides B, 4, 7 and 8

6R-Configuration was assigned to three new ceramides isolated from human skin such as ceramide B [1, (2S,3R,4E,6R)-6-hydroxy-N-(30′- hydroxytriacontanoyl)-4-sphingenine], ceramide 8 [2, (2S,3R,4E,6R)-6-hydroxy-N- (tetracosanoyl)-4-sphingenine] and ceramide 4 {3, (2S,3R,4E,6R)-6-hydroxy-N- [(30′-linoleoyloxy)triacontanoyl]-4-sphingenine}. (6R,2′ R)-Configuration was given to another ceramide in human skin, ceramide 7 [4, (2S,3R,4E,6R,2′ R)-6-hydroxy-N-(2′-hydroxytetracosanoyl)-4- sphingenine]. These assignments were made possible by enzymatic preparation of the enantiomers of 1-pentadecyn-3-ol and those of 2-hydroxytetracosanoic acid. Wiley-VCH Verlag GmbH & Co. KGaA, 2005.

Selective N-acylation of amino alcohols

The present invention provides an efficient method for the production of N-acyl amino alcohols via the selective acylation of the free amines of amino alcohols by reacting with an organic acid or a salt thereof with an alkyl sulfonyl chloride or an alkyl phenyl sulfonyl chloride, in an organic solvent and in the presence of an organic base, to form the corresponding mixed anhydride, followed by reacting the mixed anhydride with an amino alcohol or a salt thereof to form the corresponding N-acyl amino alcohol.