54401-43-3Relevant academic research and scientific papers
Molecular and Crystal Structures of 4-Cyano-3(2H)-Furanones and Structural Effects in 1H NMR Spectra
Afonin,Vashchenko,Volostnykh,Stepanov,Mal’kina
, p. 979 - 989 (2019)
Features of the molecular structure in crystals of a series of functionalized 4-cyano-3(2H)-furanones with a spiro-cyclohexane substituent or two methyl groups at position 2 of the furanone ring and also an aryl or heteroaryl substituent at position 5 are
A domino reaction of α,β-acetylenic λ-hydroxy nitriles with arenecarboxylic acids: An unexpected facile shortcut to 4-cyano-3(2 H)-furanones
Trofimov, Boris A.,Shemyakina, Olesya A.,Malkina, Anastasiya G.,Ushakov, Igor A.,Kazheva, Olga N.,Alexandrov, Grigorii G.,Dyachenko, Oleg A.
supporting information; experimental part, p. 3200 - 3203 (2010/10/03)
(Figure Presented) An unexpected facile domino reaction of α,β-acetylenic λ-hydroxy nitriles with arenecarboxylic acids (Et3N, MeCN, 20-25 °C, 48 h) affords 4-cyano-3(2H)-furanones in 67-86% yield. The reaction is triggered by the addition of a
