5441-73-6

Usage

Uses

Used in Pharmaceutical Industry:
2-methyl-5-phenyl-1H-pyrrole-3-carboxylic acid is used as a building block for the synthesis of various pharmaceuticals and biologically active compounds due to its versatile chemical structure and potential therapeutic properties.
Used in Antimicrobial Applications:
2-methyl-5-phenyl-1H-pyrrole-3-carboxylic acid is used as an antimicrobial agent for its potential to combat various microorganisms, contributing to the development of new antibiotics and antimicrobial drugs.
Used in Antiviral Applications:
2-methyl-5-phenyl-1H-pyrrole-3-carboxylic acid is used as an antiviral agent for its potential to inhibit viral replication and infection, making it a candidate for the development of new antiviral medications.
Used in Anti-inflammatory Applications:
2-methyl-5-phenyl-1H-pyrrole-3-carboxylic acid is used as an anti-inflammatory agent for its potential to reduce inflammation and alleviate pain, indicating its use in the development of new anti-inflammatory drugs.
Used in Pain Relief Applications:
2-methyl-5-phenyl-1H-pyrrole-3-carboxylic acid is used as a pain-relieving agent for its potential to provide analgesic effects, making it a candidate for the development of new pain management medications.

Upstream product

• 3652-48-0 ethyl 2-methyl-5-phenyl-1H-pyrrole-3-carboxylate 
• 52313-46-9 ethyl 2-acetyl-4-oxo-4-phenylbutanoate 
• 89201-10-5 α-Phenacyl-acetessigsaeure-aethylester 
• 14205-43-7 tert-butyl 3-aminocrotonate 
• 70-11-1 α-bromoacetophenone 

Downstream Products

• 130850-57-6 4-Bromo-2-methyl-5-phenyl-1H-pyrrole-3-carboxylic acid 
• 1220830-66-9 N-(3-(4-(3-chlorophenyl)piperazin-1-yl)propyl)-2-methyl-5-phenyl-1H-pyrrole-3-carboxamide 
• 1220830-81-8 N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-2-methyl-5-phenyl-1H-pyrrole-3-carboxamide 
• 1220830-96-5 N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)-2-methyl-5-phenyl-1H-pyrrole-3-carboxamide 
• 1220831-12-8 N-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)-2-methyl-5-phenyl-1H-pyrrole-3-carboxamide 
• 1220831-21-9 N-(4-(4-(2,3-dimethylphenyl)piperazin-1-yl)butyl)-2-methyl-5-phenyl-1H-pyrrole-3-carboxamide 

Relevant academic research and scientific papers

Arylpiperazine-containing pyrrole 3-carboxamide derivatives targeting serotonin 5-HT2A, 5-HT2C, and the serotonin transporter as a potential antidepressant

Arylpiperzine-containing pyrrole 3-carboxamide derivatives were synthesized and evaluated as novel antidepressant compounds. The various analogues were efficiently prepared and bio-assayed for binding to 5-HT2A, 5-HT2C receptor, and

One-step continuous flow synthesis of highly substituted pyrrole-3-carboxylic acid derivatives via in situ hydrolysis of tert-butyl esters

The first one-step, continuous flow synthesis of pyrrole-3-carboxylic acids directly from tert-butyl acetoacetates, amines, and 2-bromoketones is reported. The HBr generated as a byproduct in the Hantzsch reaction was utilized in the flow method to hydrolyze the t-butyl esters in situ to provide the corresponding acids in a single microreactor. The protocol was used in the multistep synthesis of pyrrole-3-carboxamides, including two CB1 inverse agonists, directly from commercially available starting materials in a single continuous process.

Oxidative Halogenation of Substituted Pyrroles with Cu(II). Part II. Bromination of some Ethyl 3-Pyrrolecarboxylates and Corresponding Acids

Ethyl 3-pyrrolecarboxylates and their corresponding acids are brominated with copper(II) bromide.The reaction afforded at 0 deg, with high-yield nuclear monobromination.