544431-10-9

Basic information

• Product Name: Acetamide, 2-cyano-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-
• Synonyms: 2-cyano-N-(5-ethyl-[1,3,4]thiadiazol-2-yl)acetamide
• CAS NO: 544431-10-9
• Molecular Formula: C7H8N4OS
• Molecular Weight: 196.233
• Mol File: 544431-10-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Acetamide, 2-cyano-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, 2-cyano-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-(544431-10-9)
• EPA Substance Registry System: Acetamide, 2-cyano-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-(544431-10-9)

Safety Data

• Hazardous Substances Data: 544431-10-9(Hazardous Substances Data)

Upstream product

• 14068-53-2 2-amino-5-ethyl-1,3,4-thiadiazole 
• 36140-83-7 1-cyanoacetyl-3,5-dimethylpyrazole 
• 105-56-6 ethyl 2-cyanoacetate 

Relevant articles and documents

Synthesis and insecticidal assessment of some innovative heterocycles incorporating a thiadiazole moiety against the cotton leafworm,: Spodoptera littoralis

New 2-cyano-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide (1) was utilized as a versatile precursor for the synthesis of various heterocycles, such as pyrrole, pyridine, coumarin, thiazole, pyrido[2′,3′:3,4]pyrazolo[5,1-c]triazine, triazolo[5,1-c]triazine, aminopyrazole, thiophene, 1,3-dithiolane, triazolo[1,5-a]pyrimidine and benzo[d]imidazole derivatives. The newly synthesized compounds were identified by IR, MS, 1H NMR, 13C NMR, DEPT, H-H COSY, HMBC, and HSQC. Representative compounds of the synthesized products were examined and estimated as insecticidal agents against the cotton leafworm, Spodoptera littoralis.

Identification of a selective inverse agonist for the orphan nuclear receptor estrogen-related receptor α

The estrogen-related receptor α (ERRα) is an orphan receptor belonging to the nuclear receptor superfamily. The physiological role of ERRα has yet to be established primarily because of lack of a natural ligand. Herein, we describe the discovery of the fi