5446-58-2

Basic information

• Product Name: N-P-TOLUENESULFONYLIMINO-3,3'-DIPROPIONIC ACID
• Synonyms: LABOTEST-BB LT00454987;N-P-TOLUENESULFONYLIMINO-3,3'-DIPROPIONIC ACID;N-P-TOLUENESULPHONYLIMINO-3,3'-DIPROPIONIC ACID;N-(2-carboxyethyl)-N-[(4-methylphenyl)sulphonyl]-beta-alanine;N-(2-Carboxyethyl)-N-[(4-methylphenyl)sulfonyl]-β-alanine
• CAS NO: 5446-58-2
• Molecular Formula: C₁₃H₁₇NO₆S
• Molecular Weight: 315.34
• EINECS: 226-660-1
• Mol File: 5446-58-2.mol
• Article Data: 3

Chemical Properties

• Melting Point: 170-173°C
• Boiling Point: 562.9°Cat760mmHg
• Flash Point: 294.2°C
• Appearance: /
• Density: 1.392g/cm³
• BRN: 2820711
• CAS DataBase Reference: N-P-TOLUENESULFONYLIMINO-3,3'-DIPROPIONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: N-P-TOLUENESULFONYLIMINO-3,3'-DIPROPIONIC ACID(5446-58-2)
• EPA Substance Registry System: N-P-TOLUENESULFONYLIMINO-3,3'-DIPROPIONIC ACID(5446-58-2)

Safety Data

• Hazardous Substances Data: 5446-58-2(Hazardous Substances Data)

Usage

General Description

N-P-Toluenesulfonylimino-3,3'-dipropionic acid is a chemical compound that belongs to the class of sulfones. It is used as a reagent in organic synthesis, particularly in the preparation of amides and esters. N-P-TOLUENESULFONYLIMINO-3,3'-DIPROPIONIC ACID is a white to off-white solid with a molecular formula of C13H15NO6S and a molecular weight of 309.33 g/mol. It is soluble in common organic solvents such as acetone, methanol, and ethanol. N-P-Toluenesulfonylimino-3,3'-dipropionic acid is known for its reactivity and ability to form stable intermediates in organic reactions, making it a valuable tool for synthetic chemists.

Upstream product

• 18773-54-1 4-methyl-N,N-diprop-2-ynylbenzenesulfonamide 
• 111-94-4 3,3'-Iminodipropionitrile 
• 3518-88-5 3,3'-imino-di-propionic acid diethyl ester 
• 98-59-9 p-toluenesulfonyl chloride 
• 2619-16-1 N,N-bis[(2-cyanoethyl)]-4-methylbenzenesulfonamide 

Downstream Products

• 112672-90-9 benzo-1,5,9-triacylododecane N,N',N''-tritosylamide 
• 35980-67-7 1,5,9-tritosyl-1,5,9-triazacyclododecane 
• 294-80-4 1,5,9-triazacyclododecane 
• 35980-62-2 1,5,9-triazacyclododecane trihydrobromide 
• 75321-10-7 3-propyl tosylate 
• 56187-12-3 N-tosyl-bis(3-hydroxypropyl)amine 
• 116073-79-1 C₆₆H₉₄N₆O₁₄S₂ 
• 116073-81-5 C₄₅H₅₇N₃O₁₂ 
• 116102-08-0 5,13-bis(4'-methoxycarbonylbenzoyl)-21-tosyl-1,9,17-trioxa-5,13,21-triazacyclotetracosane 
• 116073-82-6 5,13,21-tris(4-carboxybenzoyl)-1,9,17-trioxa-5,13,21-triazacyclotetracosane 
• 116073-83-7 C₄₂H₄₈Cl₃N₃O₉ 
• 116073-77-9 C₄₁H₅₃N₃O₁₁S 
• 116073-78-0 C₄₁H₅₁Cl₂N₃O₉S 
• 116073-67-7 21-tosyl-1,9,17-trioxa-5,13,21-triazacyclotetracosane-6,12-dione 

Relevant articles and documents

Oxidation of Alkynyl Boronates to Carboxylic Acids, Esters, and Amides

A general efficient protocol was developed for the synthesis of carboxylic acids, esters, and amides through oxidation of alkynyl boronates, generated directly from terminal alkynes. This protocol represents the first example of C(sp)?B bond oxidation. This approach displays a broad substrate scope, including aryl and alkyl alkynes, and exhibits excellent functional group tolerance. Water, primary and secondary alcohols, and amines are suitable nucleophiles for this transformation. Notably, amino acids and peptides can be used as nucleophiles, providing an efficient method for the synthesis and modification of peptides. The practicability of this methodology was further highlighted by the preparation of pharmaceutical molecules.

SYNTHESIS OF 2,3,5,6-TETRAHYDRO-1H,4H,11cH-3a,6a,11b-TRIAZABENZANTHRACENE (5) AND X-RAY CRYSTAL STRUCTURE DETERMINATIONS OF (5), HEXAHYDRO-1H,4H,7H,9bH-3a,6a,9a-TRIAZAPHENALENE (1), BENZO-1,5,9-TRIAZADODECANE N,N',N''-TRITOSYLAMIDE, AND OF 1,5,9-TRIAZADODECANE N,N'N''-TRITOSYLAMID

The synthesis of 2,3,5,6-tetrahydro-1H,4H,11cH-3a,6a,11b-triazabenzanthracene (5) is described.X-ray crystal structure determinations on hexahydro-1H,4H,7H,9bH-3a,6a,9a-triazaphenalene (1) and its benzoanaloque (5) show them to adopt differing conformations; the reasons for this are discussed.