544706-66-3

Upstream product

• 106-51-4 p-benzoquinone 
• 1066-54-2 trimethylsilylacetylene 
• 54655-07-1 lithium trimethylsilylacetylenide 

Downstream Products

• 544706-67-4 cis-1,4-diacetoxy-1,4-bis(trimethylsilylethynyl)cyclohexa-2,5-diene 
• 544706-70-9 acetic acid 4-acetoxy-1,4-diethynyl-cyclohexa-2,5-dienyl ester 
• 24936-01-4 cis-1,4-Diaethinyl-cis-1,4-dihydroxy-1,4-dihydrobenzol 

Relevant academic research and scientific papers

Synthesis of strained pyridine-containing cyclyne via reductive aromatization

The Sonogashira-Hagihara coupling reactions of 2,6-diiodopyridine and cis-3,6-diethynyl-3,6-dimethoxycyclohexa-1,4-diene or cis-9,10-diethynyl-9,10- dimethoxy-9,10-dihydroanthracene gave macrocyclic compounds having alternating 2,6-diethynylpyridine and 3,6-dimethoxycyclohexa-1,4-diene segments. Transformation of the C3-symmetric 2,6-diethynylpyridine-based cyclotrimer was efficiently achieved using tin-mediated reductive aromatization under mild conditions.

Synthesis of buta-1,3-diyne-bridged macrocycles with (Z)-1,4-diethynyl-1,4-dimethoxycyclohexa-2,5-diene as the building block

(Z)-1,4-Diethynyl-1,4-dimethoxycyclohexa-2,5-diene has been used as a building block for the synthesis of two novel macrocycles containing buta-1,3-diyne units as bridges. The tetrayne derivative 5c has been structurally characterized by single crystal X-ray crystallographic data. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003.