54504-73-3

Basic information

• Product Name: 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)ethyl bis(4-chlorophenoxy)acetate
• CAS NO: 54504-73-3
• Molecular Formula: C₂₃H₂₀Cl₂N₄O₆
• Molecular Weight: 519.3341
• Mol File: 54504-73-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 743.2°C at 760 mmHg
• Flash Point: 403.3°C
• Density: 1.46g/cm³
• Vapor Pressure: 5.83E-22mmHg at 25°C
• Refractive Index: 1.649
• CAS DataBase Reference: 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)ethyl bis(4-chlorophenoxy)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)ethyl bis(4-chlorophenoxy)acetate(54504-73-3)
• EPA Substance Registry System: 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)ethyl bis(4-chlorophenoxy)acetate(54504-73-3)

Safety Data

• Hazardous Substances Data: 54504-73-3(Hazardous Substances Data)

Upstream product

• 29815-94-9 Bis-(p-chlorophenoxy)-essigsaeure 
• 519-37-9 7-(2-hydroxyethyl)theophylline 

Relevant articles and documents

Chemistry of phenoxyacetic acid esters of oxyalkyltheophyllines and 1-(theophyllin-7-yl)-ethyl-2-[2-(p-chlorophenoxy)-2-methylpropionate] (Etofylline clofibrate), a novel antilipaemic agent

Esters of phenoxyacetic acids and oxyalkyltheophyllines were prepared as potential antihyperlipaemics. The basic idea was to ameliorate the known antilipaemic potency of phenoxyacetic acids and that of clofibric acid as the best known representative, respectively, by using alcoholic ester components with therapeutical efficacy of their own and to expand their therapeutical spectrum. Syntheses and preparative routes of these esters are presented. 1-(Theophyllin-7-yl)-ethyl-2-[2-(p-chlorophenoxy)-2-methyl-propionate] (ML 1024; etofylline clofibrate; Duolip) was selected for further investigations. Characteristics and spectroscopic data of ML 1024 are described.