5452-59-5

Basic information

• Product Name: 6-methoxy-5-(4-methoxyphenoxy)-8-nitroquinoline
• Synonyms: 5-[p-Anisyloxy]-6-methoxy-8-nitroquinoline; 6-Methoxy-5-(4-methoxyphenoxy)-8-nitroquinoline
• CAS NO: 5452-59-5
• Molecular Formula: C₁₇H₁₄N₂O₅
• Molecular Weight: 326.3035
• Mol File: 5452-59-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 488.1°C at 760 mmHg
• Flash Point: 249°C
• Density: 1.319g/cm³
• Vapor Pressure: 3.36E-09mmHg at 25°C
• Refractive Index: 1.635
• CAS DataBase Reference: 6-methoxy-5-(4-methoxyphenoxy)-8-nitroquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 6-methoxy-5-(4-methoxyphenoxy)-8-nitroquinoline(5452-59-5)
• EPA Substance Registry System: 6-methoxy-5-(4-methoxyphenoxy)-8-nitroquinoline(5452-59-5)

Safety Data

• Hazardous Substances Data: 5452-59-5(Hazardous Substances Data)

Upstream product

• 64992-86-5 5-chloro-6-methoxy-8-nitro-quinoline 
• 150-76-5 4-methoxy-phenol 
• 85-81-4 6-methoxy-8-nitroquinoline 
• 7357-66-6 N-(5-bromo-4-methoxy-2-nitrophenyl)acetamide 
• 6943-73-3 N-(3-bromo-4-methoxyphenyl)acetamide 
• 5347-15-9 5-bromo-6-methoxy-8-nitroquinoline 
• 1122-93-6 potassium p-methoxyphenolate 

Downstream Products

• 82329-84-8 2-{4-[6-Methoxy-5-(4-methoxy-phenoxy)-quinolin-8-ylamino]-pentyl}-isoindole-1,3-dione 
• 61895-55-4 6-methoxy-5-(4-methoxy-phenoxy)-[8]quinolylamine 

Relevant articles and documents

5-phenoxy primaquine analogs and the tetraoxane hybrid as antimalarial agents

The rapid emergence of drug resistance to the current antimalarial agents has led to the urgent need for the discovery of new and effective compounds. In this work, a series of 5-phenoxy primaquine analogs with 8-aminoquinoline core (7a–7h) was synthesize